Botha, C.J. (Christoffel Jacobus)Venter, ElnaUniversity of Pretoria. Faculty of Veterinary Science. Dept. of Paraclinical Sciences. Section Pharmacology and Toxicology2008-12-192008-12-192002Botha, CJ & Venter, E 2002, 'Plants poisonous to livestock Southern Africa (CD-ROM)' University of Pretoria, Faculty of Veterinary Science, Dept. of Paraclinical Sciences, Section Pharmacology and Toxicology, Pretoria, South Africa.http://hdl.handle.net/2263/8489Colour photos. Final web-ready size: JPEG, 72 ppi. Photo 1: 24.3 kb; Photo 2: 13.1 kb; Photo 3: 7.35 kb; Photo 4: 8.52 kb. Original TIFF file housed at the Dept. of Paraclinical Sciences, Section Pharmacology and Toxicology, University of Pretoria.DISTRIBUTION: Grows everywhere, but especially in vleis. Flowers whenever it rains. Western Cape around Boland, Eastern Cape, Karoo, Free State, Gauteng and Mpumalanga. Not found in Kwazulu – Natal. Botanical description: General: A soft-leaved, decumbent to erect herbaceous plant about 40 cm high. A stout woody rhizome with numerous stems. Leaves: Alternate, crowded at the base. Flowers: Yellow disc florets. White to pale purplish pink ray florets. Seed: A round woolly puffball seed head. Seeds are woolly.TOXIC PRINCIPLE: A furanosesquiterpenoid.SYNDROMES: Hepatogenous photosensitivity primarily due to liver parenchymal damage.SYSTEMS AFFECTED: Liver and respiratory systems.CLINICAL SIGNS: • Signs can occur within 3 days of introduction to camp. • Icterus, secondary photosensitivity • Colic, rumen stasis, constipation, tenesmus• Dyspnoea and “lugdikkop” • Foam at nose, marked inspiration and expiration.NECROPSY: Macroscopical findings: • Clear macroscopic damage to liver. Liver swollen, friable and yellow brown. Accentuated lobulation (dark red zones in most gives a mosaic appearance). • Icterus, gall bladder oedema.• Nephrosis.HISTOPATHOLOGY: • Liver - Lesions tend to be peripheral in acute poisoning • Subacute - range of changes• Send in liver specimens for histopathology.©University of Pretoria. Dept. of Paraclinical Sciences, Section Pharmacology and Toxicology (Original and digital). Provided for educational purposes only. It may not be downloaded, reproduced or distributed in any format without written permission of the original copyright holder. Any attempt to circumvent the access controls placed on this file is a violation of copyright laws and is subject to criminal prosecution. Please contact the collection administrator for copyright issues.Plant poisoningToxicologyPlant poisoning in animalsPoisonous plantsHepatogenousPhotosensitivityFuranosesquiterpenoidPoisonous plants -- Toxicology -- Africa, SouthernVeterinary toxicologyStill Image