Young, E.Basson, P.A.Weiss, K.E.South Africa. Dept. of Agricultural Technical ServicesTustin, R.C.De Lange, M.Reinecke, R.K.Walker, Jane B.De Kock, V.E.2015-07-082015-07-0820131970Young, E, Basson, PA & Weiss, KE 1970, 'Experimental infection of game animals with lumpy skin disease virus (prototype strain Neethling)’, Onderstepoort Journal of Veterinary Research, vol. 37, no. 2, pp. 79-87.http://hdl.handle.net/2263/46329The journals have been scanned in colour with a HP 5590 scanner; 600 dpi. Adobe Acrobat v.11 was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.Calves of a giraffe, an impala, two buffaloes, and two adult black wildebeests were artificially infected with the Neethling type of lumpy skin disease virus. The giraffe and impala died with typical symptoms and lesions of the disease. Virological examinations confirmed the presence of lumpy skin disease virus in lesions of these animals. Histopathological studies revealed microscopic lesions typical of those reported in cattle suffering from lumpy skin disease. Both intracytoplasmic and intranuclear inclusions were noticed in various cell types and some additional histopathological changes are reported. Neither the wildebeests nor the buffaloes reacted clinically to artificial infection and they failed to show a rise in antibody titre subsequently.en©South Africa. Dept. of Agricultural Technical Services (original). ©University of Pretoria. Dept. of Library Services (digital).Veterinary medicineVeterinary reportsSouth AfricaVeterinary medicine -- South AfricaLumpy skin diseaseCattle -- Virus diseasesPoxvirus diseasesArticle