Antigenic and genetic analysis of canine parvoviruses in southern Africa

dc.contributor.authorSteinel, A.
dc.contributor.authorParrish, C.R.
dc.contributor.authorTruyen, U.
dc.contributor.editorVerwoerd, Daniel Wynand
dc.contributor.upauthorVan Vuuren, Moritz
dc.contributor.upauthorVenter, Estelle Hildegard
dc.date.accessioned2012-11-06T09:20:45Z
dc.date.available2012-11-06T09:20:45Z
dc.date.created2012
dc.date.issued1998
dc.descriptionThe articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat X Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.en
dc.description.abstractCanine parvovirus (CPV) is a significant pathogen of domestic and free-ranging carnivores all over the world . It suddenly appeared at the end of the 1970s and most likely emerged as a variant of the well known feline panleukopenia virus (FPV). During its adaptation to the new host, the domestic dog, the virus has changed its antigenic profile twice giving rise to two new antigenic types, CPV-2a and CPV-2b. These new types have replaced the original type CPV-2 in the United States of America, Europe and Japan. However, no data about the prevalence of the new antigenic types on the African continent are available. In this study, 128 recent parvovirus isolates from South Africa and Namibia were antigenically typed with type-specific monoclonal antibodies. No original CPV-2 viruses were found and its complete replacement by the new antigenic types conforms to the situation in other parts of the world. The predominant strain found in southern Africa was CPV-2b (66 %), which differs from the situation in Europe and Japan where CPV-2a is the most prevalent type. Analysis of the capsid protein DNA-sequences of four selected African isolates gave no hint of a specific African parvovirus lineage.en
dc.description.librarianmn2012en
dc.description.sponsorshipGesellschaft for kynologische Forschung (GKF). German Academic Exchange Service (DAAD). Ludwig-Maximilians University, Munich.en
dc.identifier.citationSteinel, A, Venter, EH, Van Vuuren, M, Parrish, CR & Truyen, U 1998, 'Antigenic and genetic analysis of canine parvoviruses in southern Africa’. Onderstepoort Journal of Veterinary Research, vol. 65, no. 4, pp. 239-242.en
dc.identifier.issn0330-2465
dc.identifier.other7003904650
dc.identifier.other7004572625
dc.identifier.otherO-6953-2014
dc.identifier.otherN-9080-2014
dc.identifier.urihttp://hdl.handle.net/2263/20370
dc.language.isoenen
dc.publisherPublished by the Agricultural Research Council, Onderstepoort Veterinary Instituteen
dc.rights© ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital).en
dc.subjectVeterinary medicineen
dc.subjectAfricaen
dc.subjectAntigenic typesen
dc.subjectCanine parvovirus (CPV)en
dc.subjectDistributionen
dc.subject.lcshVeterinary medicine -- South Africa
dc.subject.lcshCanine parvovirus infectionsen
dc.subject.lcshDogs -- Virus diseasesen
dc.titleAntigenic and genetic analysis of canine parvoviruses in southern Africaen
dc.typeArticleen

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