Correlation between thyroid ultrasound and histology in patients with indeterminate cytology results : a local experience

dc.contributor.authorKhalushi, R.E.
dc.contributor.authorJackson, Brandon Spencer
dc.contributor.authorMokoena, Taole
dc.contributor.emailbrandon.jackson@up.ac.zaen_ZA
dc.date.accessioned2021-09-07T06:17:51Z
dc.date.available2021-09-07T06:17:51Z
dc.date.issued2020-09
dc.description.abstractBACKGROUND : Thyroid nodules are common. Most patients with indeterminate fine needle aspiration cytology (FNAC) results are subjected to thyroidectomy for fear of malignancy. However, only 20–30% of these cases are found to be malignant. The aim was to determine the value of thyroid ultrasound in diagnosing malignancy in patients with indeterminate fine needle aspiration cytology results in our practice. Fine needle aspiration was performed after ultrasound, thereby preventing architectural distortion of the nodule and to ensure that the most suspicious nodule was biopsied. METHODS : A retrospective review of records of patients who presented to two University of Pretoria academic hospitals, in South Africa, from 2001 to 2015 with nodular thyroid goitre was undertaken. Patients had a thyroid ultrasound scan, FNAC and had undergone thyroid surgery. RESULTS : Records of 104 patients were retrospectively evaluated. Patients were predominantly female (93.3%). Histology report was available for 101 of the 104 patient records. Malignancy was identified in 23 (22.8%). The overall sensitivity and specificity of thyroid image reporting and data system (TIRADS) score in this study were 69.5% and 61.5% respectively. The TIRADS classification had high sensitivity amongst the 26 patients with indeterminate cytology, with sensitivity and specificity of 85.7% and 52.6% respectively, however it was not statistically significant (p = 0.28). CONCLUSION : There was poor identification of malignancy with the use of ultrasound TIRADS classification in cases of indeterminate FNAC results, Bethesda III or IV, in our study. This is probably related to the diversity of ultrasonographers in our practice. It is recommended that there should be a dedicated thyroid ultrasonographer for a better and consistent TIRADS classification that surgeons can rely on for guiding surgical intervention.en_ZA
dc.description.departmentSurgeryen_ZA
dc.description.librarianam2021en_ZA
dc.description.urihttp://www.sajs.org.za/index.php/sajsen_ZA
dc.identifier.citationKhalushi, R.E., Jackson, B.S. & Mokoena, T. 2020, 'Correlation between thyroid ultrasound and histology in patients with indeterminate cytology results: a local experience', South African Journal of Surgery, vol. 58, no. 3, pp. 133-137.en_ZA
dc.identifier.issn0038-2361 (print)
dc.identifier.issn2078-5151 (online)
dc.identifier.other10.17159/2078-5151/2020/v58n2a3200
dc.identifier.urihttp://hdl.handle.net/2263/81669
dc.language.isoenen_ZA
dc.publisherHealth and Medical Publishing Groupen_ZA
dc.rights© 2020 The Author(s). Open Access article distributed under the terms of the Creative Commons License [CC BY-NC-ND 4.0].en_ZA
dc.subjectThyroiden_ZA
dc.subjectNoduleen_ZA
dc.subjectUltrasounden_ZA
dc.subjectIndeterminateen_ZA
dc.subjectCytologyen_ZA
dc.subjectHistologyen_ZA
dc.subjectCanceren_ZA
dc.subjectFine needle aspiration cytology (FNAC)en_ZA
dc.titleCorrelation between thyroid ultrasound and histology in patients with indeterminate cytology results : a local experienceen_ZA
dc.typeArticleen_ZA

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Khalushi_Correlation_2020.pdf
Size:
310.73 KB
Format:
Adobe Portable Document Format
Description:
Article

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description: