Cardiac glycoside poisoning in sheep caused by Urginea physodes (Jacq.) Bak. and the isolated physodine A

dc.contributor.authorNel, P.W.
dc.contributor.authorJordaan, P.
dc.contributor.authorAnderson, L.A.P.
dc.contributor.authorKellerman, T. Stephanus
dc.contributor.authorReid, Clare
dc.contributor.authorSchultz, R.A. (Rowena Anitra)
dc.contributor.editorBigalke, R.D.
dc.date.accessioned2014-11-17T08:34:31Z
dc.date.available2014-11-17T08:34:31Z
dc.date.created2014
dc.date.issued1987
dc.descriptionThe articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.en_US
dc.description.abstractUrginea physodes (Jacq.) Bak., a species closely related to or possibly synonymous with U. pusilla, is described and its distribution given. Four bufadienolides were isolated from U. physodes and the approximated LD₅₀ and cumulative effect of some of them determined in guinea pigs. The most toxic one proved to be mildly cumulative. Typical signs of acute cardiac glycoside poisoning, involving the locomotory, gastro-intestinal, respiratory and cardiac systems, were seen in the field cases and/or were experimentally induced by the plant. Similar signs could also be induced by injecting the isolated bufadienolide, physodine A, to a sheep.en_US
dc.description.librarianlmchunu2014en_US
dc.description.librarianmn2014
dc.identifier.citationNel, PW, Schultz, RA, Jordaan, P, Anderson, LAP, Kellerman, TS & Reid, C 1987, 'Cardiac glycoside poisoning in sheep caused by Urginea physodes (Jacq.) Bak. and the isolated physodine A’, Onderstepoort Journal of Veterinary Research, vol. 54, no. 4, pp. 641-644.en_US
dc.identifier.issn0330-2465
dc.identifier.urihttp://hdl.handle.net/2263/42588
dc.language.isoenen_US
dc.publisherPublished by the Government Printer, Pretoria.en_US
dc.rights©ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Dept. of Library Services (digital).en_US
dc.subjectVeterinary medicineen_US
dc.subject.lcshVeterinary medicine -- South Africa
dc.titleCardiac glycoside poisoning in sheep caused by Urginea physodes (Jacq.) Bak. and the isolated physodine Aen_US
dc.typeArticleen_US

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