Studies on the development of a vaccine against bovine ephemeral fever

dc.contributor.authorTheodoridis, A.
dc.contributor.authorBoshoff, S.E.T.
dc.contributor.authorBotha, M.J.
dc.contributor.editorDe Lange, M.
dc.contributor.editorBigalke, R.D.
dc.contributor.editorHowell, P.G.
dc.contributor.editorReinecke, R.K.
dc.contributor.editorWalker, Jane B.
dc.contributor.otherDe Kock, V.E.
dc.date.accessioned2016-07-07T09:10:53Z
dc.date.available2016-07-07T09:10:53Z
dc.date.created2016
dc.date.issued1973
dc.descriptionThe articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.en_ZA
dc.description.abstractBovine ephemeral fever virus of low passage level (5th to 8th) in tissue culture has proved to be more antigenic for cattle than higher passage level (17th to 19th) or mouse-brain-adapted virus. However, the neutralizing antibody response appears to be short-lived and therefore probably provides inadequate protection. Similar results were obtained when ephemeral fever virus of both low and high passage level was adsorbed onto aluminium hydroxide and inoculated into cattle. Emulsions of ephemeral fever virus of both low and high passage level in Freund's incomplete mineral oil adjuvant induced high neutralizing antibody titres in vaccinated cattle. These antibodies were detectable for at least a year and the animals were found to be immune when infected with virulent bovine ephemeral fever virus.en_ZA
dc.identifier.citationTheodoridis, A, Boshoff, SET & Botha, MJ 1973, 'Studies on the development of a vaccine against bovine ephemeral fever’, Onderstepoort Journal of Veterinary Research, vol. 40, no. 3, pp. 77-82.en_ZA
dc.identifier.issn0330-2465
dc.identifier.urihttp://hdl.handle.net/2263/54186
dc.language.isoenen_ZA
dc.publisherPretoria : The Government Printeren_ZA
dc.rights© 1973 ARC - Onderstepoort and Faculty of Veterinary Science. University of Pretoria (original). © 2016 University of Pretoria. Department of Library Services (digital).en_ZA
dc.subjectEphemeral feveren_ZA
dc.subject.lcshVeterinary medicine -- South Africa
dc.subject.lcshCattle -- Diseasesen_ZA
dc.subject.lcshVaccinesen_ZA
dc.titleStudies on the development of a vaccine against bovine ephemeral feveren_ZA
dc.typeArticleen_ZA

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