Seroprevalence and factors associated with Coxiella burnetii exposure in goats in Moretele

dc.contributor.authorMagadu, Rungano
dc.contributor.authorThompson, P.N. (Peter N.)
dc.contributor.emailrungano.magadu@up.ac.zaen_US
dc.date.accessioned2023-10-27T05:43:34Z
dc.date.available2023-10-27T05:43:34Z
dc.date.issued2023-04
dc.description.abstractInfection with Coxiella burnetii causes significant economic impact and poses zoonotic risk to people exposed to livestock, yet few studies in South Africa have assessed seroprevalence of C. burnetii infection and no information is available for goats. Very little information is available regarding risk factors and outcomes of C. burnetii infection in peri-urban farming areas where widespread mixing of ruminants occurs. This study estimated the seroprevalence of C. burnetii infection among communally farmed goats in an area adjacent to the densely populated Gauteng province. Sera were collected from 216 goats in 39 herds, and questionnaires were completed to establish management practices as potential risk factors. C. burnetii antibody testing was done by ELISA. Thirty two out of 216 goats tested positive for C. burnetii antibodies and the overall seroprevalence, adjusted for sampling weights and clustering, was 18.4% (95% confidence interval [CI]: 12.2% – 23.5%). The intraclass correlation coefficient was 0.06, indicating low-to-moderate clustering. Multiple logistic regression showed age was significantly associated with seropositivity, with higher seroprevalence in animals ≥ 19 months old (26%) than animals ≤ 6 months old (6%) (odds ratio [OR]: 6.6; p = 0.010). We concluded C. burnetii infection is common in goats in Moretele and a potential cause of abortion in goats and poses the potential zoonotic disease risk.en_US
dc.description.departmentProduction Animal Studiesen_US
dc.description.urihttp://www.ojvr.orgen_US
dc.identifier.citationMagadu, R., Thompson, P.N. Seroprevalence and factors associated with Coxiella burnetii exposure in goats in Moretele. Onderstepoort Journal of Veterinary Research 2023 Apr 4; 90(1): e1-e7. doi: 10.4102/ojvr.v90i1.2071.en_US
dc.identifier.issn2219-0635 (online)
dc.identifier.issn0030-2465 (print)
dc.identifier.other10.4102/ojvr.v90i1.2071
dc.identifier.urihttp://hdl.handle.net/2263/93094
dc.language.isoenen_US
dc.publisherBMJ Publishingen_US
dc.rights© 2023. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.en_US
dc.subjectCoxiella burnetiien_US
dc.subjectGoatsen_US
dc.subjectSeroprevalenceen_US
dc.subjectZoonosisen_US
dc.subjectSDG-03: Good health and well-beingen_US
dc.subjectEnzyme-linked immunosorbent assay (ELISA)en_US
dc.subjectRisk factorsen_US
dc.titleSeroprevalence and factors associated with Coxiella burnetii exposure in goats in Moreteleen_US
dc.typeArticleen_US

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