Epidemiology of influenza virus types and subtypes in South Africa, 2009-2012

dc.contributor.authorCohen, Adam L.
dc.contributor.authorHellferscee, Orienka
dc.contributor.authorPretorius, Marthi Andréa
dc.contributor.authorTreurnicht, Florette K.
dc.contributor.authorWalaza, Sibongile
dc.contributor.authorMadhi, Shabir A.
dc.contributor.authorGroome, Michelle
dc.contributor.authorDawood, Halima
dc.contributor.authorVariava, Ebrahim
dc.contributor.authorKahn, Kathleen
dc.contributor.authorWolter, Nicole
dc.contributor.authorVon Gottberg, Anne
dc.contributor.authorTempia, Stefano
dc.contributor.authorVenter, Marietjie
dc.contributor.authorCohen, Cheryl
dc.date.accessioned2014-08-14T10:12:48Z
dc.date.available2014-08-14T10:12:48Z
dc.date.issued2014-07
dc.descriptionThis information has been presented at Options for the Control of Influenza VIII, Cape Town, South Africa, September 5–9, 2013.en_US
dc.description.abstractTo determine clinical and epidemiologic differences between influenza caused by different virus types and subtypes, we identified patients and tested specimens. Patients were children and adults hospitalized with confirmed influenza and severe acute respiratory illness (SARI) identified through active, prospective, hospital-based surveillance from 2009–2012 in South Africa. Respiratory specimens were tested, typed, and subtyped for influenza virus by PCR. Of 16,005 SARI patients tested, 1,239 (8%) were positive for influenza virus. Patient age and co-infections varied according to virus type and subtype, but disease severity did not. Case-patients with influenza B were more likely than patients with influenza A to be HIV infected. A higher proportion of case-patients infected during the first wave of the 2009 influenza pandemic were 5–24 years of age (19%) than were patients infected during the second wave (9%). Although clinical differences exist, treatment recommendations do not differ according to subtype; prevention through vaccination is recommended.en_US
dc.description.librarianam2014en_US
dc.description.sponsorshipThe Centers for Disease Control and Prevention, Atlanta, Georgia, USA, and the National Institute for Communicable Diseases, Johannesburg, South Africa.en_US
dc.description.urihttp://www.cdc.gov/eiden_US
dc.identifier.citationCohen, AL, Hellferscee, O, Pretorius, M, Treurnicht, F, Walaza, S, Madhi, S, Groome, M, Dawood, H, Variava, E, Kahn, K, Wolter, N, Von Gottberg, A, Tempia, S, Venter, M & Cohen, C 2014, 'Epidemiology of influenza virus Types and subtypes in South Africa, 2009-2012', Emerging Infectious Diseases, vol. 20, no. 7, pp. 1162-1169.en_US
dc.identifier.issn1080-6040 (print)
dc.identifier.issn1080-6059 (online)
dc.identifier.other10.3201/eid2007.131869
dc.identifier.urihttp://hdl.handle.net/2263/41288
dc.language.isoenen_US
dc.publisherCoordinating Center for Infectious Diseases, Centers for Disease Control and Preventionen_US
dc.rightsCoordinating Center for Infectious Diseases, Centers for Disease Control and Preventionen_US
dc.subjectEpidemiologyen_US
dc.subjectVirusen_US
dc.subjectPatientsen_US
dc.subjectSouth Africa (SA)en_US
dc.subjectInfluenza types and subtypesen_US
dc.subjectSevere acute respiratory illness (SARI)en_US
dc.titleEpidemiology of influenza virus types and subtypes in South Africa, 2009-2012en_US
dc.typeArticleen_US

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