Epidemiology of influenza virus types and subtypes in South Africa, 2009-2012
dc.contributor.author | Cohen, Adam L. | |
dc.contributor.author | Hellferscee, Orienka | |
dc.contributor.author | Pretorius, Marthi Andréa | |
dc.contributor.author | Treurnicht, Florette K. | |
dc.contributor.author | Walaza, Sibongile | |
dc.contributor.author | Madhi, Shabir A. | |
dc.contributor.author | Groome, Michelle | |
dc.contributor.author | Dawood, Halima | |
dc.contributor.author | Variava, Ebrahim | |
dc.contributor.author | Kahn, Kathleen | |
dc.contributor.author | Wolter, Nicole | |
dc.contributor.author | Von Gottberg, Anne | |
dc.contributor.author | Tempia, Stefano | |
dc.contributor.author | Venter, Marietjie | |
dc.contributor.author | Cohen, Cheryl | |
dc.date.accessioned | 2014-08-14T10:12:48Z | |
dc.date.available | 2014-08-14T10:12:48Z | |
dc.date.issued | 2014-07 | |
dc.description | This information has been presented at Options for the Control of Influenza VIII, Cape Town, South Africa, September 5–9, 2013. | en_US |
dc.description.abstract | To determine clinical and epidemiologic differences between influenza caused by different virus types and subtypes, we identified patients and tested specimens. Patients were children and adults hospitalized with confirmed influenza and severe acute respiratory illness (SARI) identified through active, prospective, hospital-based surveillance from 2009–2012 in South Africa. Respiratory specimens were tested, typed, and subtyped for influenza virus by PCR. Of 16,005 SARI patients tested, 1,239 (8%) were positive for influenza virus. Patient age and co-infections varied according to virus type and subtype, but disease severity did not. Case-patients with influenza B were more likely than patients with influenza A to be HIV infected. A higher proportion of case-patients infected during the first wave of the 2009 influenza pandemic were 5–24 years of age (19%) than were patients infected during the second wave (9%). Although clinical differences exist, treatment recommendations do not differ according to subtype; prevention through vaccination is recommended. | en_US |
dc.description.librarian | am2014 | en_US |
dc.description.sponsorship | The Centers for Disease Control and Prevention, Atlanta, Georgia, USA, and the National Institute for Communicable Diseases, Johannesburg, South Africa. | en_US |
dc.description.uri | http://www.cdc.gov/eid | en_US |
dc.identifier.citation | Cohen, AL, Hellferscee, O, Pretorius, M, Treurnicht, F, Walaza, S, Madhi, S, Groome, M, Dawood, H, Variava, E, Kahn, K, Wolter, N, Von Gottberg, A, Tempia, S, Venter, M & Cohen, C 2014, 'Epidemiology of influenza virus Types and subtypes in South Africa, 2009-2012', Emerging Infectious Diseases, vol. 20, no. 7, pp. 1162-1169. | en_US |
dc.identifier.issn | 1080-6040 (print) | |
dc.identifier.issn | 1080-6059 (online) | |
dc.identifier.other | 10.3201/eid2007.131869 | |
dc.identifier.uri | http://hdl.handle.net/2263/41288 | |
dc.language.iso | en | en_US |
dc.publisher | Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention | en_US |
dc.rights | Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention | en_US |
dc.subject | Epidemiology | en_US |
dc.subject | Virus | en_US |
dc.subject | Patients | en_US |
dc.subject | South Africa (SA) | en_US |
dc.subject | Influenza types and subtypes | en_US |
dc.subject | Severe acute respiratory illness (SARI) | en_US |
dc.title | Epidemiology of influenza virus types and subtypes in South Africa, 2009-2012 | en_US |
dc.type | Article | en_US |