Experimental verification and validation of a computer model for light–tissue interaction
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Date
Authors
Karsten, Aletta Elizabeth
Singh, Ann
Braun, Max Willi Hermann
Journal Title
Journal ISSN
Volume Title
Publisher
Springer
Abstract
Laser light is frequently used in both diagnostics and treatment of patients. For any laser treatment to be effective it is important to deliver the correct dose at the treatment site. Human skin scatters and absorbs laser light in the visible wavelength region, which results in a decrease in fluence some distance into the skin. Computer simulations can be used to predict the fluence at the treatment site. Liquid and solid phantoms were prepared and the optical properties were measured. These values were then used as input values to a commercial software package simulating the different layers of skin representing phantoms. The transmission and reflected fractions of the different phantoms were measured with an integrating sphere and compared with the computer simulations. The results showed very good agreement with the measured values and the model can therefore be used with confidence to predict fluence at any treatment site inside the skin.
Description
Keywords
Laser treatment, Light–tissue interaction, Fluence
Sustainable Development Goals
Citation
Karsten, AE, Singh, A & Braun, MW 2012, 'Experimental verification and validation of a computer model for light–tissue interaction', Lasers in Medical Science, vol. 27, no. 1, pp. 79-86, doi: 10.1007/s10103-011-0926-x.