The use of saponin spore vaccine for inoculation against anthrax in South Africa

dc.contributor.authorSterne, Max
dc.contributor.authorNicol, J.
dc.contributor.authorRobinson, E.M.
dc.contributor.editorDu Toit, P.J.
dc.date.accessioned2016-07-12T06:42:11Z
dc.date.available2016-07-12T06:42:11Z
dc.date.created2016
dc.date.issued1939
dc.descriptionThe articles have been scanned in colour with a HP scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to final presentation PDF-Format.en_ZA
dc.descriptionIncludes bibliographical referencesen_ZA
dc.description.abstract(1) Virulent anthrax strains incorporated in saponin retained much of their virulence, and could not be used in vaccines. (2) Italian and American commercial saponin vaccines examined by us did not contain virulent strains. (3) Not more than 0·6 to 1·0 percent saponin should he used, where the dose for bovines is 1·0 c.c. and for sheep 0·5 c.c. (4) Saponin reduced slightly the virulence of vaccine strains for guinea-pigs. (5) Glycerine enhanced the virulence of vaccine strains for guinea-pigs. (6) A large-scale field test failed to show any difference between saponin vaccine and ordinary spore vaccine. (7) Laboratory tests on sheep, showed that saponin considerably increased the immunizing power of ordinary vaccine strains. This phenomenon could also be demonstrated in the case of an avirulent uncapsulated variant. (8) It is suggested that saponin should be used with mild strains to improve immunity, rather than with strong strains to reduce virulence.en_ZA
dc.description.librarianab2018
dc.format.extent24 pages : tables, graphsen_ZA
dc.identifier.citationSterne, M, Robinson, EM & Nicol, J 1939, 'The use of saponin spore vaccine for inoculation against anthrax in South Africa', Onderstepoort Journal of Veterinary Science and Animal Industry, vol. 12, no. 2, pp. 279-302en_ZA
dc.identifier.issn0330-2456
dc.identifier.urihttp://hdl.handle.net/2263/55102
dc.language.isoenen_ZA
dc.publisherPretoria : Government Printeren_ZA
dc.rights©ARC-Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Department of Library Services (digital)en_ZA
dc.subjectSaponin spore vaccineen_ZA
dc.subjectAnthrax -- South Africaen_ZA
dc.subjectVaccinationen_ZA
dc.subjectVaccinesen_ZA
dc.subject.lcshVeterinary medicine -- South Africa
dc.titleThe use of saponin spore vaccine for inoculation against anthrax in South Africaen_ZA
dc.typeArticleen_ZA

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