Risk factors for, and molecular epidemiology and clinical outcomes of, carbapenem- and polymyxin-resistant Gram-negative bacterial infections in pregnant women, infants, and toddlers : a systematic review and meta-analyses

dc.contributor.authorOsei Sekyere, John
dc.contributor.authorReta, Melese Abate
dc.contributor.authorFourie, Petrus Bernardus
dc.date.accessioned2022-02-18T10:59:49Z
dc.date.issued2021-10
dc.descriptionSUPPORTING INFORMATION: Figure S1. Literature search strategy, inclusion and exclusion criteria employed to arrive at the articles used in this study.en_ZA
dc.descriptionFigure S2. The isolation rate of Gram-negative bacterial species obtained from infants and pregnant women per country.en_ZA
dc.descriptionFigure S3. Mortality rates associated with carbapenem resistance in infants per country.en_ZA
dc.descriptionFigure S4. The count and isolation rates of Gram-negative bacterial species obtained from pregnant women and infants per country.en_ZA
dc.descriptionFigure S5. The count of Gram-negative bacteria clones infecting or colonizing infants and pregnant women per country.en_ZA
dc.descriptionFigure S6. Carbapenem and polymyxin resistance rates in Gram-negative bacteria isolated from infants and pregnant women.en_ZA
dc.descriptionFigure S7. Carbapenemases detected in Gram-negative bacteria per country.en_ZA
dc.descriptionFigure S8. Risk factors associated with carbapenem and polymyxin-resistant Gram-negative bacteria in neonates and pregnant women.en_ZA
dc.descriptionTable S1. Data on the epidemiology, risk factors, clinical outcomes, resistance mechanisms and rates, and the prevalence of carbapenem-resistant Gram-negative bacteria infecting or colonizing infants.en_ZA
dc.descriptionTable S2. Data on the epidemiology, risk factors, clinical outcomes, resistance mechanisms and rates, and the prevalence of carbapenem-resistant Gram-negative bacteria infecting or colonizing pregnant women.en_ZA
dc.descriptionTable S3. Data on the epidemiology, risk factors, clinical outcomes, resistance mechanisms and rates, and the prevalence of polymyxin-resistant Gram-negative bacteria infecting or colonizing infants and pregnant women.en_ZA
dc.descriptionTable S4. Statistical analyses of the pooled data showing association between age, species, countries, resistance mechanisms, clones, risk factors, and mortalities.en_ZA
dc.description.abstractPlease read abstract in the article.en_ZA
dc.description.departmentMedical Microbiologyen_ZA
dc.description.embargo2022-07-02
dc.description.librarianhj2022en_ZA
dc.description.sponsorshipThe National Health Laboratory Service (NHLS)en_ZA
dc.description.urihttps://nyaspubs.onlinelibrary.wiley.com/journal/17496632en_ZA
dc.identifier.citationOsei Sekyere, J., Reta, M.A. & Fourie, P.B. 2021, 'Risk factors for, and molecular epidemiology and clinical outcomes of, carbapenem- and polymyxin-resistant Gram-negative bacterial infections in pregnant women, infants, and toddlers: a systematic review and meta-analyses', Annals of the New York Academy of Sciences, vol. 1502, no. 1, pp. 54-71, doi: 10.1111/nyas.14650.en_ZA
dc.identifier.issn0077-8923 (print)
dc.identifier.issn1749-6632 (online)
dc.identifier.other10.1111/nyas.14650
dc.identifier.urihttp://hdl.handle.net/2263/84073
dc.language.isoenen_ZA
dc.publisherWileyen_ZA
dc.rights© 2021 New York Academy of Sciences. This is the pre-peer reviewed version of the following article : 'Risk factors for, and molecular epidemiology and clinical outcomes of, carbapenem- and polymyxin-resistant Gram-negative bacterial infections in pregnant women, infants, and toddlers: a systematic review and meta-analyses', Annals of the New York Academy of Sciences, vol. 1502, no. 1, pp. 54-71, 2021, doi : 10.1111/nyas.14650. The definite version is available at : https://nyaspubs.onlinelibrary.wiley.co m/journal/17496632.en_ZA
dc.subjectCarbapenemen_ZA
dc.subjectPolymyxinen_ZA
dc.subjectColistinen_ZA
dc.subjectCarbapenemaseen_ZA
dc.subjectAntibiotic resistanceen_ZA
dc.subjectPregnant womenen_ZA
dc.subjectInfantsen_ZA
dc.subjectNeonatesen_ZA
dc.titleRisk factors for, and molecular epidemiology and clinical outcomes of, carbapenem- and polymyxin-resistant Gram-negative bacterial infections in pregnant women, infants, and toddlers : a systematic review and meta-analysesen_ZA
dc.typePostprint Articleen_ZA

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