Amaurosis in sheep resulting from treatment with rafoxanide
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Date
Authors
Prozesky, Leon
Pienaar, J.G.
Journal Title
Journal ISSN
Volume Title
Publisher
Pretoria : The Government Printer
Abstract
Amaurosis occurred in sheep on various farms in the Republic of South Africa after treatment with rafoxanide. Histopathological examination revealed a status spongiosus of varying severity in the central nervous system in all the cases, having a predilection for certain areas such as the periventricular area of the lateral ventricles, optic tracts, lateral geniculates and optic fasciculi. The retina was the only ocular tissue affected and lesions observed in the retina included necrosis of nerve cells in the ganglionic layer. In chronic cases of amaurosis this layer showed a complete absence of nerve cells. The possible pathogenesis of the lesions and their differentiation from those found in certain plant toxicoses are discussed.
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Keywords
Veterinary medicine, Amaurosis, Rafoxanide
Sustainable Development Goals
Citation
Prozesky, L & Pienaar, JG 1977, 'Amaurosis in sheep resulting from treatment with rafoxanide’, Onderstepoort Journal of Veterinary Research, vol. 44, no. 4, pp. 257-260.