Relation between macrophage migration inhibition and immunity to Brucella abortus in guinea-pigs
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Date
Authors
Cameron, Colin McKenzie
Van Rensburg, J.J.
Engelbrecht, Maria M.
Journal Title
Journal ISSN
Volume Title
Publisher
Published by The Government Printer, Pretoria
Abstract
A soluble protein antigen was prepared from Brucella melitensis Rev I with which macrophage migration inhibition (MMI) assays were successfully done using guinea-pig peritoneal exudate cells. By comparing the MMI, agglutinin response and immunity of groups and of individual guinea-pigs which had been immunized with either B. melitensis Rev I live vaccine or B. melitensis Rev I inactivated antigen, an association between the MMI and resistance to infection was demonstrated.
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Keywords
Veterinary medicine
Sustainable Development Goals
Citation
Cameron, CM, Van Rensburg, JJ & Engelbrecht, MM 1976, 'Relation between macrophage migration inhibition and immunity to Brucella abortus in guinea-pigs’, Onderstepoort Journal of Veterinary Research, vol. 43, no. 4, pp. 175-84.