Enzymatic activation of Clostridium perfringens epsilon prototoxin and some biological properties of activated toxin
| dc.contributor.author | Worthington, R.W. | |
| dc.contributor.author | Mulders, M.S.G. | |
| dc.contributor.author | Van Rensburg, J.J. | |
| dc.contributor.editor | De Lange, M. | |
| dc.contributor.editor | Bigalke, R.D. | |
| dc.contributor.editor | Cameron, Colin McKenzie | |
| dc.contributor.editor | Walker, Jane B. | |
| dc.contributor.editor | Verster, Anna J.M. | |
| dc.contributor.other | De Kock, V.E. | |
| dc.date.accessioned | 2016-07-06T10:10:50Z | |
| dc.date.available | 2016-07-06T10:10:50Z | |
| dc.date.created | 2016 | |
| dc.date.issued | 1973 | |
| dc.description | The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. | en_ZA |
| dc.description.abstract | Maximal activation of Clostridium perfringens epsilon toxin was only achieved by the combined action of trypsin and chymotrypsin. Impure preparations of trypsin, presumably containing small amounts of chymotrypsin were more efficient in activating prototoxin than pure trypsin. Activated toxin was readily absorbed by brain tissue and smaller amounts were possibly absorbed by kidney tissue. Other tissues absorbed only very small amounts of toxin. Injection of mice with toxoid 3 h prior to challenge with toxin increased their resistance 32 times. | en_ZA |
| dc.identifier.citation | Worthington, RW, Mulders, MSG & Van Rensburg, JJ 1973, ‘Enzymatic activation of Clostridium perfringens epsilon prototoxin and some biological properties of activated toxin’, Onderstepoort Journal of Veterinary Research, vol. 40, no. 4, pp. 153-156. | en_ZA |
| dc.identifier.issn | 0330-2465 | |
| dc.identifier.uri | http://hdl.handle.net/2263/53693 | |
| dc.language.iso | en | en_ZA |
| dc.publisher | Published by the Government Printer, Pretoria | en_ZA |
| dc.rights | ©1973 ARC-Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©2016 University of Pretoria. Department of Library Services (digital). | en_ZA |
| dc.subject | Veterinary medicine | en_ZA |
| dc.subject.lcsh | Veterinary medicine -- South Africa | |
| dc.title | Enzymatic activation of Clostridium perfringens epsilon prototoxin and some biological properties of activated toxin | en_ZA |
| dc.type | Article | en_ZA |