Kasabach-Merritt-like syndrome in a dog secondary to isolated splenic haemangiomatosis

dc.contributor.authorPazzi, Paolo
dc.contributor.authorClift, Sarah Jane
dc.contributor.authorHartman, Marthinus Jacobus
dc.contributor.authorO'Dell, Nicolize
dc.contributor.emailpaolo.pazzi@up.ac.zaen_ZA
dc.date.accessioned2021-09-15T06:53:45Z
dc.date.available2021-09-15T06:53:45Z
dc.date.issued2020-06
dc.description.abstractA 13-year-old intact male miniature schnauzer presented with lethargy, distended abdomen and pallor. Pancytopenia was identified on complete blood count with a severe thrombocytopenia. Cavitatory severe splenomegaly was identified on abdominal ultrasound. Two weeks of immunosuppressive therapy had no effect on the thrombocytopenia and a splenectomy was performed. The platelet count returned to normal within 24 hours of splenectomy. Isolated splenic haemangiomatosis was confirmed on histopathology and immunohistochemistry. The anaemia and severe thrombocytopenia in conjunction with the ultrasound findings and histopathology are characteristic of Kasabach-Merritt syndrome in people. This is the first case of Kasabach-Merritt-like syndrome described in the dog.en_ZA
dc.description.departmentCompanion Animal Clinical Studiesen_ZA
dc.description.departmentParaclinical Sciencesen_ZA
dc.description.librarianhj2021en_ZA
dc.description.urihttps://bvajournals.onlinelibrary.wiley.com/journal/20526121en_ZA
dc.identifier.citationPazzi, P., Clift, S.J., Hartman, M.J. & O'Dell, N. 2020, 'Kasabach-Merritt-like syndrome in a dog secondary to isolated splenic haemangiomatosis', Vet Record Case Reports, vol. 8, no. 2, e001090.en_ZA
dc.identifier.issn2052-6121 (online)
dc.identifier.other10.1136/vetreccr-2020-001090
dc.identifier.urihttp://hdl.handle.net/2263/81832
dc.language.isoenen_ZA
dc.publisherWileyen_ZA
dc.rights© 2020 British Veterinary Association. This is the pre-peer reviewed version of the following article : 'Kasabach-Merritt-like syndrome in a dog secondary to isolated splenic haemangiomatosis', Vet Record Case Reports, vol. 8, no. 2, e001090, 2020, doi : 10.1136/vetreccr-2020-001090. The definite version is available at : https://bvajournals.onlinelibrary.wiley.com/journal/20526121.en_ZA
dc.subjectDogs (Canis familiaris)en_ZA
dc.subjectSpleenen_ZA
dc.subjectHaemangiomaen_ZA
dc.subjectAnaemiaen_ZA
dc.subjectThrombocytopeniaen_ZA
dc.titleKasabach-Merritt-like syndrome in a dog secondary to isolated splenic haemangiomatosisen_ZA
dc.typePostprint Articleen_ZA

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