Perspectives on peripheral neuropathy as a consequence of metformin-induced vitamin B12 deficiency in T2DM

dc.contributor.authorAhmed, Marwan Awad
dc.contributor.authorMuntingh, George L.
dc.contributor.authorRheeder, Paul
dc.date.accessioned2017-09-12T09:52:09Z
dc.date.available2017-09-12T09:52:09Z
dc.date.issued2017-08-27
dc.description.abstractPeripheral neuropathy (PN) is a primary complication of type 2 diabetes mellitus (T2DM) and a direct manifestation of vitamin B12 deficiency. Examining the effects of metformin use on PN status became imperative following clinical studies that showed the vitamin B12-lowering effect of the medication. The complexity of the topic and the inconsistency of the results warrant consideration of topic-specific perspectives for better understanding of the available evidence and more appropriate design of future studies.en_ZA
dc.description.departmentInternal Medicineen_ZA
dc.description.departmentPharmacologyen_ZA
dc.description.librarianam2017en_ZA
dc.description.urihttps://www.hindawi.com/journals/ijeen_ZA
dc.identifier.citationAhmed, M.A., Muntingh, G.L. & Rheeder, P. 2017, 'Perspectives on peripheral neuropathy as a consequence of metformin-induced vitamin B12 deficiency in T2DM', International Journal of Endocrinology, vol. 2017, art. no. 2452853, pp. 1-6.en_ZA
dc.identifier.issn1687-8337 (print)
dc.identifier.issn1687-8345 (online)
dc.identifier.other10.1155/2017/2452853
dc.identifier.urihttp://hdl.handle.net/2263/62241
dc.language.isoenen_ZA
dc.publisherHindawi Publishing Corporationen_ZA
dc.rights© 2017 Marwan A. Ahmed et al. This is an open access article distributed under the Creative Commons Attribution License.en_ZA
dc.subjectPeripheral neuropathy (PN)en_ZA
dc.subjectType 2 diabetes mellitus (T2DM)en_ZA
dc.subjectVitamin B12 deficiencyen_ZA
dc.subjectHyperhomocysteinemiaen_ZA
dc.subjectRisken_ZA
dc.subjectFolateen_ZA
dc.subjectMellitusen_ZA
dc.subjectPrevalenceen_ZA
dc.subjectHomocysteineen_ZA
dc.subjectRacial differencesen_ZA
dc.subjectCobalamin deficiencyen_ZA
dc.titlePerspectives on peripheral neuropathy as a consequence of metformin-induced vitamin B12 deficiency in T2DMen_ZA
dc.typeArticleen_ZA

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