The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum

dc.contributor.authorSoma-Pillay, Priya
dc.contributor.authorPillay, R.
dc.contributor.authorWong, T.Y.
dc.contributor.authorMakin, J.D. (Jennifer Dianne)
dc.contributor.authorPattinson, Robert Clive
dc.contributor.emailpriya.somapillay@up.ac.zaen_ZA
dc.date.accessioned2018-04-20T10:54:59Z
dc.date.available2018-04-20T10:54:59Z
dc.date.issued2018-09
dc.description.abstractBACKGROUND : The retinal microcirculation provides a unique view of microvessel structure by means of non-invasive, retinal image analysis. The aim of the study was to compare the retinal vessel caliber at delivery and one-year post-partum between women who have had pre-eclampsia during pregnancy to a normotensive control group. METHODS : Digital photos of the eye were taken at delivery and one-year post-partum. Retinal vessels were analysed and summarised as the corrected central retinal arteriolar equivalent and corrected central retinal venular equivalent. RESULTS : The corrected central retinal arteriolar equivalent and corrected central retinal venular equivalent were significantly lower in the pre-eclamptic group compared to the control group both at delivery and one-year post-partum (p < 0.001). CONCLUSION : Retinal artery and venular caliber changes that occur during pregnancies affected by pre-eclampsia persist for up to one-year post-partum. These changes may reflect a permanent, long-term microvascular dysfunction and may be useful as a biomarker of future vascular risk.en_ZA
dc.description.departmentObstetrics and Gynaecologyen_ZA
dc.description.librarianhj2018en_ZA
dc.description.urihttp://journals.sagepub.com/home/obmen_ZA
dc.identifier.citationSoma-Pillay, P., Pillay, R., Wong, T.Y. et al. 2018, 'The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum', Obstetric Medicine, vol. 11, no. 3, pp. 116-120.en_ZA
dc.identifier.issn1753-495X (print)
dc.identifier.issn1753-4968 (online)
dc.identifier.other10.1177/1753495X17745727
dc.identifier.urihttp://hdl.handle.net/2263/64670
dc.language.isoenen_ZA
dc.publisherSageen_ZA
dc.rights© The Author(s) 2018en_ZA
dc.subjectRetinal microvascular calibreen_ZA
dc.subjectPre-eclampsiaen_ZA
dc.subjectHypertensionen_ZA
dc.titleThe effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partumen_ZA
dc.typePostprint Articleen_ZA

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