The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum
dc.contributor.author | Soma-Pillay, Priya | |
dc.contributor.author | Pillay, R. | |
dc.contributor.author | Wong, T.Y. | |
dc.contributor.author | Makin, J.D. (Jennifer Dianne) | |
dc.contributor.author | Pattinson, Robert Clive | |
dc.contributor.email | priya.somapillay@up.ac.za | en_ZA |
dc.date.accessioned | 2018-04-20T10:54:59Z | |
dc.date.available | 2018-04-20T10:54:59Z | |
dc.date.issued | 2018-09 | |
dc.description.abstract | BACKGROUND : The retinal microcirculation provides a unique view of microvessel structure by means of non-invasive, retinal image analysis. The aim of the study was to compare the retinal vessel caliber at delivery and one-year post-partum between women who have had pre-eclampsia during pregnancy to a normotensive control group. METHODS : Digital photos of the eye were taken at delivery and one-year post-partum. Retinal vessels were analysed and summarised as the corrected central retinal arteriolar equivalent and corrected central retinal venular equivalent. RESULTS : The corrected central retinal arteriolar equivalent and corrected central retinal venular equivalent were significantly lower in the pre-eclamptic group compared to the control group both at delivery and one-year post-partum (p < 0.001). CONCLUSION : Retinal artery and venular caliber changes that occur during pregnancies affected by pre-eclampsia persist for up to one-year post-partum. These changes may reflect a permanent, long-term microvascular dysfunction and may be useful as a biomarker of future vascular risk. | en_ZA |
dc.description.department | Obstetrics and Gynaecology | en_ZA |
dc.description.librarian | hj2018 | en_ZA |
dc.description.uri | http://journals.sagepub.com/home/obm | en_ZA |
dc.identifier.citation | Soma-Pillay, P., Pillay, R., Wong, T.Y. et al. 2018, 'The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum', Obstetric Medicine, vol. 11, no. 3, pp. 116-120. | en_ZA |
dc.identifier.issn | 1753-495X (print) | |
dc.identifier.issn | 1753-4968 (online) | |
dc.identifier.other | 10.1177/1753495X17745727 | |
dc.identifier.uri | http://hdl.handle.net/2263/64670 | |
dc.language.iso | en | en_ZA |
dc.publisher | Sage | en_ZA |
dc.rights | © The Author(s) 2018 | en_ZA |
dc.subject | Retinal microvascular calibre | en_ZA |
dc.subject | Pre-eclampsia | en_ZA |
dc.subject | Hypertension | en_ZA |
dc.title | The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum | en_ZA |
dc.type | Postprint Article | en_ZA |