EEG brain wave activity at rest and during evoked attention in children with attention-deficit/hyperactivity disorder and effects of methylphenidate

dc.contributor.authorThomas, Bianca Lee
dc.contributor.authorViljoen, Margaretha
dc.date.accessioned2016-04-25T10:50:55Z
dc.date.available2016-04-25T10:50:55Z
dc.date.issued2016
dc.description.abstractOBJECTIVE : The aim of this study was to assess baseline EEG brain wave activity in children with attention-deficit/hyperactivity disorder (ADHD) and to examine the effects of evoked attention and methylphenidate on this activity. METHOD : Children with ADHD (n = 19) were tested while they were stimulant free and during a period in which they were on stimulant (methylphenidate) medication. Control subjects (n = 18) were tested once. EEG brain wave activity was tested both at baseline and during focussed attention. Attention was evoked and EEG brain wave activity was determined by means of the BioGraph Infiniti biofeedback apparatus. RESULTS : The main finding of this study was that control subjects and stimulant-free children with ADHD exhibited the expected reactivity in high alpha-wave activity (11-12 Hz) from baseline to focussed attention; however, methylphenidate appeared to abolish this reactivity. CONCLUSION : Methylphenidate attenuates the normal cortical response to a cognitive challenge.en_ZA
dc.description.departmentPsychiatryen_ZA
dc.description.librarianhb2016en_ZA
dc.description.urihttp://www.karger.com/Journal/Home/224082en_ZA
dc.identifier.citationThomas, BL & Viljoen, M 2016, 'EEG brain wave activity at rest and during evoked attention in children with attention-deficit/hyperactivity disorder and effects of methylphenidate', Neuropsychobiology, vol. 73, no. 1, pp. 16-22.en_ZA
dc.identifier.issn0302-282X (print)
dc.identifier.issn1423-0224 (online)
dc.identifier.other10.1159/000441523
dc.identifier.urihttp://hdl.handle.net/2263/52149
dc.language.isoenen_ZA
dc.publisherKargeren_ZA
dc.rights© 2016 S. Karger AG, Baselen_ZA
dc.subjectMethylphenidateen_ZA
dc.subjectRitalinen_ZA
dc.subjectHigh alpha activityen_ZA
dc.subjectFocussed attentionen_ZA
dc.subjectCortical reactivityen_ZA
dc.subjectCognitive stressoren_ZA
dc.subjectAttention deficit hyperactivity disorder (ADHD)en_ZA
dc.subjectElectroencephalogram (EEG)en_ZA
dc.titleEEG brain wave activity at rest and during evoked attention in children with attention-deficit/hyperactivity disorder and effects of methylphenidateen_ZA
dc.typePostprint Articleen_ZA

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