Screening of the venoms of two Parabuthus scorpion species on isolated cardiomyocytes
| dc.contributor.author | Van Aarde, M.N. | |
| dc.contributor.author | Van Rooyen, J.M. | |
| dc.contributor.author | Van Aswegen, G. | |
| dc.contributor.editor | Verwoerd, Daniel Wynand | |
| dc.date.accessioned | 2013-08-27T07:25:32Z | |
| dc.date.available | 2013-08-27T07:25:32Z | |
| dc.date.created | 2013 | |
| dc.date.issued | 1996 | |
| dc.description | The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat X Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. | en |
| dc.description.abstract | Crude, diluted venoms of Parabuthus transvaalicus and P. granulatus were tested on isolated cardiomyocytes. Ventricular myocytes were subjected to hypercontractility tests and whole-cell voltage clamp. Both venoms had a profound influence on the hypercontractility of cardiomyocytes, which was markedly decreased when they were pre-absorbed with commercial antiserum. Whole-cell clamp results showed an increase in the sodium current, and a retardation of the time course of inactivation, implicating the presence of an a toxin in both venoms. | en |
| dc.description.librarian | mn2013 | |
| dc.identifier.citation | Van Aarde, MN, Van Rooyen, JM & Van Aswegen, G 1996, 'Screening of the venoms of two Parabuthus scorpion species on isolated cardiomyocytes’. Onderstepoort Journal of Veterinary Research, vol. 63, no. 2, pp. 127-130. | en |
| dc.identifier.issn | 0330-2465 | |
| dc.identifier.uri | http://hdl.handle.net/2263/22070 | |
| dc.language.iso | en | en |
| dc.publisher | Published by the Agricultural Research Council, Onderstepoort Veterinary Institute | en |
| dc.rights | © ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital). | en |
| dc.subject | Veterinary medicine | en |
| dc.subject | Cardiomyocytes | en |
| dc.subject | Parabuthus granulatus | en |
| dc.subject | Parabuthus transvaalicus | en |
| dc.subject | Scorpions | en |
| dc.subject | Venom | en |
| dc.subject.lcsh | Veterinary medicine -- South Africa | |
| dc.title | Screening of the venoms of two Parabuthus scorpion species on isolated cardiomyocytes | en |
| dc.type | Article | en |