Subcellular localization of the nonstructural protein NS3 of African horsesickness virus

dc.contributor.authorStoltz, M.A.
dc.contributor.authorVan der Merwe, Christiaan F.
dc.contributor.authorCoetzee, J.
dc.contributor.editorVerwoerd, Daniel Wynand
dc.contributor.upauthorHuismans, H. (Henk), 1942-
dc.date.accessioned2013-08-15T10:51:55Z
dc.date.available2013-08-15T10:51:55Z
dc.date.created2013
dc.date.issued1996
dc.descriptionThe articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat X Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.en
dc.description.abstractThe subcellular localization of the minor nonstructural protein NS3 of African horsesickness virus (AHSV) has been investigated by means of immunogold electron-microscopical analysis. NS3 was observed in perturbed regions of the plasma membrane of AHSV-infected VERO cells, and its presence appears to be associated with events of viral release. These events are budding, whereby released viruses acquire fragments from the host-cell membrane, as well as by the extrusion of nonenveloped particles through the cell membrane. The membrane association of NS3 was confirmed by its detection in the disrupted plasma membranes of cells infected with an NS3 baculovirus recombinant. The absence of NS3 on intact cell membranes suggests that the protein is not exposed extracellularly.en
dc.description.librarianmn2013
dc.identifier.citationStoltz, MA, Van der Merwe, CF, Coetzee, J & Huismans, H 1996, 'Subcellular localization of the nonstructural protein NS3 of African horsesickness virus’. Onderstepoort Journal of Veterinary Research, vol. 63, no. 1, pp. 57-61.en
dc.identifier.issn0330-2465
dc.identifier.urihttp://hdl.handle.net/2263/22034
dc.language.isoenen
dc.publisherPublished by the Agricultural Research Council, Onderstepoort Veterinary Instituteen
dc.rights© ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital).en
dc.subjectVeterinary medicineen
dc.subjectAfrican horsesickness virus (AHSV)en
dc.subjectNon-structural protein 3 (NS3)en
dc.subjectNS3en
dc.subjectSubcellular localizationen
dc.subject.lcshVeterinary medicine -- South Africa
dc.subject.lcshAfrican horse sickness -- South Africaen
dc.titleSubcellular localization of the nonstructural protein NS3 of African horsesickness virusen
dc.typeArticleen

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