A case report of post-radiotherapy c-MYC-positive angiosarcoma of the breast
| dc.contributor.author | Retter, Edna | |
| dc.contributor.author | Benn, Carol-Ann | |
| dc.contributor.author | Maske, Christopher | |
| dc.contributor.author | Rapoport, Bernardo Leon | |
| dc.date.accessioned | 2023-05-08T12:40:32Z | |
| dc.date.available | 2023-05-08T12:40:32Z | |
| dc.date.issued | 2022-02-07 | |
| dc.description.abstract | Angiosarcoma of the breast is an unusual malignancy and carries a poor prognosis, with a 5-year overall survival rate ranging from 27 to 48%. Radiotherapy-induced angiosarcoma (RIAS) of the breast is very uncommon, with an estimated incidence of 1 in 1,000 cases of breasts treated with radiotherapy for breast cancer. The increase in radiotherapy usage may lead to an increased incidence of RIAS. A case presentation of a 67-year-old patient with tubular adenocarcinoma of the left breast who developed c-MYC-positive RIAS of the breast is presented. The patient was successfully treated with surgery. We presented a classic case of c-MYC RIAS. c-MYC was reported to be positive in RIAS and other types of angiosarcomas. Clinical examination and early detection of RIAS breast angiosarcoma is vital to improving outcomes in these patients. | en_US |
| dc.description.department | Immunology | en_US |
| dc.description.librarian | am2023 | en_US |
| dc.description.sponsorship | The Cancer Association of South Africa (CANSA) and the National Research Foundation (NRF) of South Africa. | en_US |
| dc.description.uri | https://www.karger.com/CRO | en_US |
| dc.identifier.citation | Retter, E., Benn, C.-A., Maske, C. et al. 2022, 'A case report of post-radiotherapy c-MYC-positive angiosarcoma of the breast', Case Reports in Oncology, vol. 15, no. 1, 62-70, doi : 10.1159/000521069. | en_US |
| dc.identifier.issn | 1662-6575 (online) | |
| dc.identifier.other | 10.1159/000521069 | |
| dc.identifier.uri | http://hdl.handle.net/2263/90596 | |
| dc.language.iso | en | en_US |
| dc.publisher | Karger Publishers | en_US |
| dc.rights | © 2022 The Author(s). This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). | en_US |
| dc.subject | Breast angiosarcoma | en_US |
| dc.subject | MYC positive | en_US |
| dc.subject | Post-radiotherapy | en_US |
| dc.subject | Radiotherapy-induced angiosarcoma (RIAS) | en_US |
| dc.title | A case report of post-radiotherapy c-MYC-positive angiosarcoma of the breast | en_US |
| dc.type | Article | en_US |