Outbreak of carbapenem-resistant Providencia rettgeri in a tertiary hospital
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Date
Authors
Tshisevhe, V.S.
Lekalakala, M.R.
Tshuma, N.
Janse van Rensburg, S.
Mbelle, Nontombi Marylucy
Journal Title
Journal ISSN
Volume Title
Publisher
Health and Medical Publishing Group
Abstract
The emergence of resistance to multiple antimicrobial agents in pathogenic bacteria is a significant public health threat, as there are limited
effective antimicrobial agents for infections caused by multidrug-resistant (MDR) bacteria. Several MDR bacteria are now frequently
detected. Carbapenem resistance in Enterobacteriaceae is often plasmid mediated, necessitating stringent infection control practices. We
describe an outbreak of carbapenem-resistant Providencia rettgeri involving 4 patients admitted to intensive care and high-care units at a
tertiary hospital. Clinical and demographic characteristics of 4 patients with carbapenem-resistant P. rettgeri were documented. All P. rettgeri
isolated in these cases had a carbapenem-resistant antibiogram, with resistance to imipenem, ertapenem and meropenem. These cases could
be epidemiologically linked. A multiprong approach, simultaneously targeting antibiotic stewardship, universal precautions and appropriate
transmission-based precaution practices, is integral to prevention and control of nosocomial infections.
Description
Keywords
Infections, Intensive care, Providencia rettgeri, Pathogenic bacteria, Multidrug-resistant (MDR), MDR bacteria, Providencia rettgeri
Sustainable Development Goals
Citation
Tshisevhe, VS, Lekalakala, MR, Tshuma, N, Janse Van Rensburg, S & Mbelle, N 2017, 'Outbreak of carbapenem-resistant Providencia rettgeri in a tertiary hospital', South African Medical Journal, vol. 107, no. 1, pp. 31-33.