Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B₁

dc.contributor.authorKellerman, T. Stephanus
dc.contributor.authorMarasas, Walter F.O. (Walter Friedrich Otto)
dc.contributor.authorThiel, P.G.
dc.contributor.authorGelderblom, W.C.A.
dc.contributor.authorCawood, M.
dc.contributor.editorVerwoerd, Daniel Wynand
dc.contributor.upauthorCoetzer, Jacobus A.W.
dc.date.accessioned2014-09-01T10:25:23Z
dc.date.available2014-09-01T10:25:23Z
dc.date.created2013
dc.date.issued1990
dc.descriptionThe articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.en
dc.description.abstractLeukoencephalomalacia (LEM) was induced by the oral administration of fumonisin B₁ (FB₁) to 2 horses: a filly received 59,5mg/kg of a 50% preparation of FB₁ administered in 21 doses of 1,25-4mg/kg over 33 days; a colt, 44,3mg/kg of 95% pure FB₁ in 20 doses of 1-4 mg/kg in 29 days. Both animals developed nervous signs such as apathy, changes in temperament, inco-ordination, walking into objects, and one showed paralysis of the lips and tongue. Characteristic lesions of LEM were present in the brains. These trials proved conclusively that FB₁ can induce LEM in horses.en
dc.description.librarianmn2014
dc.identifier.citationKellerman, TS, Marasas, WFO, Thiel, PG, Gelderblom, WCA, Cawood, M & Coetzer, JAW 1990, 'Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B₁’, Onderstepoort Journal of Veterinary Research, vol. 57, no. 4, pp. 269-275.en
dc.identifier.issn0330-2465
dc.identifier.urihttp://hdl.handle.net/2263/41861
dc.language.isoenen
dc.publisherPublished by the Government Printer, Pretoria.en
dc.rights©South Africa. Dept. of Agricultural Technical Services. ©University of Pretoria. Dept. of Library Services (digital).en
dc.subjectVeterinary medicineen
dc.subject.lcshVeterinary medicine -- South Africa
dc.titleLeukoencephalomalacia in two horses induced by oral dosing of fumonisin B₁en
dc.typeArticleen

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1990 Onderstepoort Journal of Veterinary Research, Volume 57, 1990
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