Prevalence of trypanosomes and selected symbionts in tsetse species of eastern Zambia

dc.contributor.authorMulenga, Gloria M.
dc.contributor.authorNamangala, Boniface
dc.contributor.authorGummow, Bruce
dc.date.accessioned2023-07-14T09:19:56Z
dc.date.available2023-07-14T09:19:56Z
dc.date.issued2022-09
dc.descriptionDATA AVAILABILITY : The data that support the findings of this study are available from the corresponding author upon reasonable request.en_US
dc.description.abstractInsect symbionts have attracted attention for their potential use as anti-parasitic gene products in arthropod disease vectors. While tsetse species of the Luangwa valley have been extensively studied, less is known about the prevalence of symbionts and their interactions with the trypanosome parasite. Polymerase chain reaction was used to investigate the presence of Wolbachia and Sodalis bacteria, in tsetse flies infected with trypanosomes (Trypanosoma vivax, Trypanosoma congolense and Trypanosoma brucei). Out of 278 captured tsetse flies in eastern Zambia, 95.3% (n = 265, 95% CI = 92.8–97.8) carried endosymbionts: Wolbachia (79.1%, 95% CI 73.9–83.8) and Sodalis (86.3%, 95% CI 81.7–90.1). Overall, trypanosome prevalence was 25.5% (n = 71, 95% CI = 20.4–30.7), 10.8% (n = 30, 95% CI 7.1–14.4) for T. brucei, 1.4% (n = 4, 95% CI = 0.4–3.6) for both T. congolense and T. vivax, and 0.7% (n = 2, 95% CI 0.1–2.6) for T. b. rhodesiense. Out of 240 tsetse flies that were infected with Sodalis, trypanosome infection was reported in 40 tsetse flies (16.7%, 95% CI = 12.0–21.4) while 37 (16.8%, 95% CI 11.9–21.8) of the 220 Wolbachia infected tsetse flies were infected with trypanosomes. There was 1.3 times likelihood of T. brucei infection to be present when Wolbachia was present and 1.7 likelihood of T. brucei infection when Sodalis was present. Overall findings suggest absence of correlation between the presence of tsetse endosymbionts and tsetse with trypanosome infection. Lastly, the presence of pathogenic trypanosomes in tsetse species examined provided insights into the risk communities face, and the importance of African trypanosomiasis in the area.en_US
dc.description.departmentProduction Animal Studiesen_US
dc.description.librarianhj2023en_US
dc.description.urihttps://www.cambridge.org/core/journals/parasitologyen_US
dc.identifier.citationMulenga, G., Namangala, B., & Gummow, B. (2022). Prevalence of trypanosomes and selected symbionts in tsetse species of eastern Zambia. Parasitology, 149(11), 1406-1410. doi:10.1017/S0031182022000804.en_US
dc.identifier.issn0031-1820 (print)
dc.identifier.issn1469-8161 (online)
dc.identifier.other10.1017/S0031182022000804
dc.identifier.urihttp://hdl.handle.net/2263/91452
dc.language.isoenen_US
dc.publisherCambridge University Pressen_US
dc.rights© The Author(s) 2022. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/).en_US
dc.subjectPrevalenceen_US
dc.subjectSymbionten_US
dc.subjectTrypanosomeen_US
dc.subjectTsetse fliesen_US
dc.subjectZambiaen_US
dc.subjectSDG-03: Good health and well-beingen_US
dc.titlePrevalence of trypanosomes and selected symbionts in tsetse species of eastern Zambiaen_US
dc.typeArticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Mulenga_Prevalence_2022.pdf
Size:
245.04 KB
Format:
Adobe Portable Document Format
Description:
Article

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: