Pittosporum viridiflorum Sims (Pittosporaceae) : a review on a useful medicinal plant native to South Africa and tropical Africa

dc.contributor.authorMadikizela, Balungile
dc.contributor.authorMcGaw, Lyndy Joy
dc.contributor.emaillyndy.mcgaw@up.ac.zaen_ZA
dc.date.accessioned2017-08-11T09:04:18Z
dc.date.issued2017-06
dc.description.abstractETHNOPHARMACOLOGICAL RELEVANCE : Pittosporum viridiflorum Sims, a Pittosporaceae species, is used extensively in African traditional medicine (ATM) by various tribes. This review is an appraisal of the information concerning the description, distribution, conservation status, traditional uses, phytochemistry, pharmacology and toxicology of this species with the aim of reconciling it with its traditional use. MATERIALS AND METHODS : A wide-ranging literature search was conducted using database platforms such as Scopus, Google Scholar, Web of Science, ScienceDirect, PubMed and books including local reports and thesis submissions. RESULTS : Ten categories to which P. viridiflorum finds use in traditional medicine (TM) were found, and they include well-being, wounds, treatment of veterinary ailments, gastrointestinal and sexually transmitted diseases, kidney, circulatory and inflammatory disorders, as well as diseases such as cancer, tuberculosis, and malaria. Pharmacological tests conducted include those investigating antimicrobial, antidiarrhoeal, antimalarial, anticancer, anti-inflammatory, antioxidant and acaricidal properties. Promising activity was shown in a number of assays. Toxicological effects have also been reported from this species. However, it is recommended to conduct a detailed toxicological study, including genotoxicity, as this has not yet been evaluated. Compound(s) with antimalarial, anticancer and acaricidal properties have been isolated from P. viridiflorum. CONCLUSIONS : The collective pharmacological and phytochemical properties of P. viridiflorum gives credence to the use of this plant species against various diseases in ATM, thus steering significant interest towards in vivo studies and further research.en_ZA
dc.description.departmentParaclinical Sciencesen_ZA
dc.description.embargo2018-06-09
dc.description.librarianhj2017en_ZA
dc.description.sponsorshipThe National Research Foundation (NRF), Pretoria, South Africa (NRF-Scarce Skills Post-doctoral Fellowship UID 96848 to BM and NRF Incentive Funding to LJM).en_ZA
dc.description.urihttp://www.elsevier.com/locate/jepen_ZA
dc.identifier.citationMadikizela, B. & McGaw, L.J. 2017, 'Pittosporum viridiflorum Sims (Pittosporaceae) : a review on a useful medicinal plant native to South Africa and tropical Africa', Journal of Ethnopharmacology, vol. 205, pp. 217-230.en_ZA
dc.identifier.issn1872-7573 (online)
dc.identifier.issn0378-8741 (print)
dc.identifier.other10.1016/j.jep.2017.05.005
dc.identifier.urihttp://hdl.handle.net/2263/61626
dc.language.isoenen_ZA
dc.publisherElsevieren_ZA
dc.rights© 2017 Elsevier B.V. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Journal of Ethnopharmacology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in Journal of Ethnopharmacology, vol. 205, pp. 217-230. 2017. doi : 10.1016/j.jep.2017.05.005.en_ZA
dc.subjectPittosporum viridiflorumen_ZA
dc.subjectStem barken_ZA
dc.subjectOleanolic aciden_ZA
dc.subjectAntioxidant activityen_ZA
dc.subjectPittosporaceaeen_ZA
dc.subjectAnticanceren_ZA
dc.subjectAcaricidalen_ZA
dc.subjectAntimalarialen_ZA
dc.subjectTriterpenoidsen_ZA
dc.subjectInhibitory propertiesen_ZA
dc.subjectAntiplasmodial activityen_ZA
dc.subjectAntimicrobial activityen_ZA
dc.subjectGlycosidesen_ZA
dc.titlePittosporum viridiflorum Sims (Pittosporaceae) : a review on a useful medicinal plant native to South Africa and tropical Africaen_ZA
dc.typePostprint Articleen_ZA

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Madikizela_Pittosporum_2017.pdf
Size:
616.12 KB
Format:
Adobe Portable Document Format
Description:
Postprint Article

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description: