M813: 1. Thyroid gland
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Clinical history : A 60 year old female patient with complaints of blushing and bronchial spasms.
On examination an abdominal tumour was found and the urinary excretion of HlAA (hydroxy-indol acetic-acid) was raised.
At operation the diagnosis of gastric carcinoid tumour was made.
Chemo- and radiotherapy was given but the patient's condition deteriorated and terminally diarrhoea was present.
Autopsy findings : 1. Medullary carcinoma of both lobes of the thyroid gland.
2. Tumour metastases in liver, lymph nodes, bones, lungs and secondary infiltration of stomach from peri-gastric lymph nodes metastases.
Diagnosis: Medullary carcinoma of the thyroid gland with widespread metastases causing diarrhoea, blushing and bronchial spasm
On examination an abdominal tumour was found and the urinary excretion of HlAA (hydroxy-indol acetic-acid) was raised.
At operation the diagnosis of gastric carcinoid tumour was made.
Chemo- and radiotherapy was given but the patient's condition deteriorated and terminally diarrhoea was present.
Autopsy findings : 1. Medullary carcinoma of both lobes of the thyroid gland.
2. Tumour metastases in liver, lymph nodes, bones, lungs and secondary infiltration of stomach from peri-gastric lymph nodes metastases.
Diagnosis: Medullary carcinoma of the thyroid gland with widespread metastases causing diarrhoea, blushing and bronchial spasm