Global trends in norovirus genotype distribution among children with acute gastroenteritis
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Date
Authors
Cannon, Jennifer L.
Bonifacio, Joseph
Bucardo, Filemon
Buesa, Javier
Bruggink, Leesa
Chan, Martin Chi-Wai
Fumian, Tulio M.
Giri, Sidhartha
Gonzalez, Mark D.
Hewitt, Joanne
Journal Title
Journal ISSN
Volume Title
Publisher
Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention
Abstract
Noroviruses are a leading cause of acute gastroenteritis
(AGE) among adults and children worldwide. Noro-
Surv is a global network for norovirus strain surveillance
among children <5 years of age with AGE. Participants in
16 countries across 6 continents used standardized protocols
for dual typing (genotype and polymerase type)
and uploaded 1,325 dual-typed sequences to the Noro-
Surv web portal during 2016–2020. More than 50% of
submitted sequences were GII.4 Sydney[P16] or GII.4
Sydney[P31] strains. Other common strains included
GII.2[P16], GII.3[P12], GII.6[P7], and GI.3[P3] viruses.
In total, 22 genotypes and 36 dual types, including GII.3
and GII.20 viruses with rarely reported polymerase
types, were detected, refl ecting high strain diversity. Surveillance
data captured in NoroSurv enables the monitoring
of trends in norovirus strains associated childhood
AGE throughout the world on a near real-time basis.
Description
Keywords
Norovirus, Children, Gastroenteritis, Genotypes, Vaccines, Capsids, Polymerase, Surveillance, NoroSurv, Dual typing, Acute gastroenteritis, P-types, Viruses, Enteric infections, Food safety, Acute gastroenteritis (AGE)
Sustainable Development Goals
Citation
Cannon, J.L., Bonifacio, J., Bucardo, F. et al. 2021, 'Global trends in norovirus genotype distribution among children with acute gastroenteritis', Emerging Infectious Diseases, vol. 27, no. 5, pp. 1438-1445.