South African field strains of Haemonchus contortus resistant to the levamisole/morantel group of anthelmintics
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Date
Authors
Van Schalkwyk, P.C.
Visser, Evelyn L.
Alves, Regina M.R.
Gerber, H.M.
Journal Title
Journal ISSN
Volume Title
Publisher
Published by the Government Printer, Pretoria.
Abstract
A strain of Haemonchus contortus from the Pietermaritzburg district of Natal was found to be resistant to levamisole (geometric mean efficacy 76,5 %), morantel (41,9 %), the benzimidazoles (oxfendazole: 33,7 %) and rafoxanide (82,0% ), but apparently fully susceptible to closantel and disophenol. In the case of ivermectin, a mean of 5.2 % of the H. contortus was not removed at a dosage of 200 µg kgˉ¹ live mass. A second strain of H. contortus, from Amsterdam in the south-eastern Transvaal, showed reduced susceptibility to levamisole (80,8%) and morantel (46,2% ), the only 2 drugs tested. This is apparently the first report of resistance to the levamisole/morantel group of anthelmintics in sheep in South Africa.
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Keywords
Veterinary medicine
Sustainable Development Goals
Citation
Van Wyk, JA, Van Schalkwyk, PC, Gerber, HM, Visser, EL, Alves, RMR & Van Schalkwyk, L 1989, 'South African field strains of Haemonchus contortus resistant to the levamisole/morantel group of anthelmintics', Onderstepoort Journal of Veterinary Research, vol. 56, no. 4, pp. 257-262.