Prior pulmonary tuberculosis is a risk factor for asymptomatic cryptococcal antigenemia in a cohort of adults with advanced human immunodeficiency virus disease
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Date
Authors
Wake, Rachel M.
Ismail, Nazir Ahmed
Ismail, Farzanah
Tiemessen, Caroline T.
Harrison, Thomas S.
Jarvis, Joseph N.
Govender, Nelesh
Journal Title
Journal ISSN
Volume Title
Publisher
Oxford University Press
Abstract
The greater mortality risk among people with advanced human immunodeficiency virus disease and cryptococcal antigenemia, despite treatment, indicates an increased susceptibility to other infections. We found that prior tuberculosis was an independent risk factor for cryptococcal antigenemia (adjusted odds ratio, 2.72; 95% confidence interval, 1.13–6.52;
P=.03) among patients with CD4 counts ,100 cells/μL.
Description
SUPPLEMENTARY DATA : Supplementary materials are available at Open Forum Infectious Diseases online. Consisting of data provided by the authors to benefit the reader, the posted materials are not copyedited and are the sole responsibility of the authors, so questions or comments should be addressed to the corresponding author.
Keywords
Advanced HIV disease, Cryptococcosis, Human immunodeficiency virus (HIV), Tuberculosis (TB), SDG-03: Good health and well-being
Sustainable Development Goals
Citation
Wake, R.M., Ismail, N.A., Omar, S.V. et al. 2022, 'Prior pulmonary tuberculosis is a risk factor for asymptomatic cryptococcal antigenemia in a cohort of adults with advanced human immunodeficiency virus disease', Open Forum Infectious Diseases, vol. 9, no. 7, pp. 1-4, doi : 10.1093/ofid/ofac202.
