Prior pulmonary tuberculosis is a risk factor for asymptomatic cryptococcal antigenemia in a cohort of adults with advanced human immunodeficiency virus disease

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Authors

Wake, Rachel M.
Ismail, Nazir Ahmed
Ismail, Farzanah
Tiemessen, Caroline T.
Harrison, Thomas S.
Jarvis, Joseph N.
Govender, Nelesh

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Journal ISSN

Volume Title

Publisher

Oxford University Press

Abstract

The greater mortality risk among people with advanced human immunodeficiency virus disease and cryptococcal antigenemia, despite treatment, indicates an increased susceptibility to other infections. We found that prior tuberculosis was an independent risk factor for cryptococcal antigenemia (adjusted odds ratio, 2.72; 95% confidence interval, 1.13–6.52; P=.03) among patients with CD4 counts ,100 cells/μL.

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SUPPLEMENTARY DATA : Supplementary materials are available at Open Forum Infectious Diseases online. Consisting of data provided by the authors to benefit the reader, the posted materials are not copyedited and are the sole responsibility of the authors, so questions or comments should be addressed to the corresponding author.

Keywords

Advanced HIV disease, Cryptococcosis, Human immunodeficiency virus (HIV), Tuberculosis (TB), SDG-03: Good health and well-being

Sustainable Development Goals

Citation

Wake, R.M., Ismail, N.A., Omar, S.V. et al. 2022, 'Prior pulmonary tuberculosis is a risk factor for asymptomatic cryptococcal antigenemia in a cohort of adults with advanced human immunodeficiency virus disease', Open Forum Infectious Diseases, vol. 9, no. 7, pp. 1-4, doi : 10.1093/ofid/ofac202.