Experimental evidence that the active principle of the poisonous plant Thesium lineatum L.f. (Santalaceae) is a bufadienolide
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Date
Authors
Anderson, L.A.P.
Joubert, J.P.J.
Kellerman, T. Stephanus
Pienaar, Barendina J.
Schultz, R.A. (Rowena Anitra)
Journal Title
Journal ISSN
Volume Title
Publisher
Published by the Government Printer, Pretoria.
Abstract
The toxicity of Thesium lineatum is confirmed in sheep. A toxic crystalline bufadienolide, with the suggested
trivial name thesiuside, has been isolated from it. This is the first cardiac glycoside to be isolated from a
member of the Santalaceae. The toxin appears to have no cumulative effect and the symptoms of intoxication
and pathology in sheep are similar to that expected from acute cardiac glycoside intoxication.
Thesium lineatum, a root parasite, is described and its distribution given.
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Keywords
Veterinary medicine
Sustainable Development Goals
Citation
Anderson, LAP, Joubert, JPJ, Schultz, RA, Kellerman, TS & Pienaar, BJ 1987, 'Experimental evidence that the active principle of the poisonous plant Thesium lineatum L.f. (Santalaceae) is a bufadienolide’, Onderstepoort Journal of Veterinary Research, vol. 54, no. 4, pp. 645-650.