Positive and bounded nonstandard finite difference scheme for the Hodgkin-Huxley equations

dc.contributor.authorAderogba, Adebayo Abiodun
dc.contributor.authorChapwanya, Michael
dc.contributor.emailm.chapwanya@up.ac.zaen_ZA
dc.date.accessioned2019-03-25T07:41:32Z
dc.date.issued2018-07
dc.description.abstractIn this work we consider the Hodgkin Huxley model in the form of a coupled system of one singularly perturbed partial differential equation and three ordinary differential equations. The existence of a small parameter, the nonlinearity and the coupling makes the numerical approximations using explicit finite difference schemes very difficult. In particular, spurious oscillations have been observed to exist. Here we propose the use of nonstandard finite difference to improve on the existing time step restrictions. In addition, we prove that the proposed scheme preserves positivity and is elementary stable. Numerical simulations will be given to support the performance of the proposed scheme.en_ZA
dc.description.departmentMathematics and Applied Mathematicsen_ZA
dc.description.embargo2019-07-01
dc.description.librarianhj2019en_ZA
dc.description.sponsorshipSouth African DST/NRF SARChI Chair on Mathematical Models and Methods in Bioengineering and Biosciences (M3B2).en_ZA
dc.description.urihttp://link.springer.com/journal/13160en_ZA
dc.identifier.citationAderogba, A.A. & Chapwanya, M. Positive and bounded nonstandard finite difference scheme for the Hodgkin–Huxley equations. Japan Journal of Industrial and Applied Mathematics (2018) 35: 773-785. https://doi.org/10.1007/s13160-018-0302-3.en_ZA
dc.identifier.issn0916-7005 (print)
dc.identifier.issn1868-937X (online)
dc.identifier.other10.1007/s13160-018-0302-3
dc.identifier.urihttp://hdl.handle.net/2263/68694
dc.language.isoenen_ZA
dc.publisherSpringeren_ZA
dc.rights© The JJIAM Publishing Committee and Springer Japan KK, part of Springer Nature 2018. The original publication is available at : http://link.springer.com/journal/13160.en_ZA
dc.subjectHodgkin-Huxley equationen_ZA
dc.subjectNon standard finite differenceen_ZA
dc.subjectExplicit schemesen_ZA
dc.subjectNerve conductionen_ZA
dc.titlePositive and bounded nonstandard finite difference scheme for the Hodgkin-Huxley equationsen_ZA
dc.typePostprint Articleen_ZA

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