Parameterisation and prediction of intra‑canal cochlear structures

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Authors

Thiselton, Joshua
Hanekom, Tania

Journal Title

Journal ISSN

Volume Title

Publisher

Springer

Abstract

Accurate 3D models of the cochlea are useful tools for research in the relationship between the electrode array and nerve fibres. The internal geometry of the cochlear canal plays an important role in understanding and quantifying that relationship. Predicting the location and shapes of the geometry is done by measuring histologic sections and fitting equations that can be used to predict parameters that fully define the geometry. A parameter sensitivity analysis is employed to prove that the size and location of the spiral lamina are the characteristics that most influence current distribution along target nerve fibres. The proposed landmark prediction method more accurately predicts the location of the points defining the spiral lamina in the apical region of the cochlea than methods used in previous modelling attempts. Thus, this technique can be used to generate 2D geometries that can be expanded to 3D models when high-resolution imaging is not available.

Description

Correction to: Annals of Biomedical Engineering (2024) 52:695–706 https://doi.org/10.1007/s10439-023-03417-5. The funding note is incomplete.

Keywords

Anatomic model, Cochlear duct, Cochlear implant, Anatomic landmarks, SDG-03: Good health and well-being, SDG-09: Industry, innovation and infrastructure

Sustainable Development Goals

SDG-03:Good heatlh and well-being
SDG-09: Industry, innovation and infrastructure

Citation

Thiselton, J., Hanekom, T. Parameterisation and Prediction of Intra-canal Cochlear Structures. Annals of Biomedical Engineering 52, 695–706 (2024). https://doi.org/10.1007/s10439-023-03417-5.