Isolation of a novel orthobunyavirus from bat flies (Eucampsipoda africana)

dc.contributor.authorJansen van Vuren, Petrus
dc.contributor.authorWiley, Michael R.
dc.contributor.authorPalacios, Gustavo
dc.contributor.authorStorm, Nadia
dc.contributor.authorMarkotter, Wanda
dc.contributor.authorBirkhead, Monica
dc.contributor.authorKemp, Alan
dc.contributor.authorPaweska, Janusz Tadeusz
dc.date.accessioned2018-02-08T11:22:16Z
dc.date.available2018-02-08T11:22:16Z
dc.date.issued2017-05
dc.description.abstractThe Bunyaviridae family comprises viruses causing diseases of public and veterinary health importance, including viral haemorrhagic and arboviral fevers. We report the isolation, identification and genome characterization of a novel orthobunyavirus, named Wolkberg virus (WBV), from wingless bat fly ectoparasites (Eucampsipoda africana) of Egyptian fruit bats (Rousettus aegyptiacus) in South Africa. Complete genome sequence data of WBV suggests it is most closely related to two bat viruses (Mojuí dos Campos and Kaeng Khoi viruses) and an arbovirus (Nyando virus) previously shown to infect humans. WBV replicates to high titres in VeroE6 and C6-36 cells, characteristic of mosquito-borne arboviruses. These findings expand our knowledge of the diversity of orthobunyaviruses and their insect vector host range.en_ZA
dc.description.departmentMedical Virologyen_ZA
dc.description.departmentMicrobiology and Plant Pathologyen_ZA
dc.description.librarianhj2018en_ZA
dc.description.sponsorshipThe project is jointly funded by the following grants awarded to: Janusz T. Paweska (CDC Global Disease Detection program, GDD 5U19 GH000571-05/96667), Wanda Markotter (South African National Research Foundation, Grant UID 91496, 92524 and 98339; Poliomyeli-tis Research Foundation, PRF Grant number 12/14) and Petrus Jansen van Vuren (South African National Research Foundation, Incentive Funding for Rated Researchers, Grant UID 85544).en_ZA
dc.description.urihttp://jgv.microbiologyresearch.org/content/journal/jgven_ZA
dc.description.uriArbovirusen_ZA
dc.identifier.citationJansen van Vuren, P., Wiley, M.R., Palacios, G. et al. 2017, 'Isolation of a novel orthobunyavirus from bat flies (Eucampsipoda africana)', Journal of General Virology, vol. 98, no. 5, pp. 935-945.en_ZA
dc.identifier.issn0022-1317 (print)
dc.identifier.issn1465-2099 (online)
dc.identifier.other10.1099/jgv.0.000753
dc.identifier.urihttp://hdl.handle.net/2263/63899
dc.language.isoenen_ZA
dc.publisherMicrobiology Societyen_ZA
dc.rights© 2017 The Authors. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.en_ZA
dc.subjectPathogen discoveryen_ZA
dc.subjectEucampsipoda africanaen_ZA
dc.subjectBat fliesen_ZA
dc.subjectOrthobunyavirusen_ZA
dc.subjectBunyaviridaeen_ZA
dc.subjectEgyptian fruit baten_ZA
dc.subjectRousettus aegyptiacusen_ZA
dc.titleIsolation of a novel orthobunyavirus from bat flies (Eucampsipoda africana)en_ZA
dc.typeArticleen_ZA

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
JansenVanVuren_Isolation_2017.pdf
Size:
2.01 MB
Format:
Adobe Portable Document Format
Description:
Article
Download

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Research Articles (Microbiology and Plant Pathology)
Research Articles (Medical Virology)
Research Articles (University of Pretoria)
Simple item page