Seven infectious bronchitis virus genotypes including South American-origin G1-11 and Asian-origin GVI-1 circulated in southern African poultry from 2010 to 2020

dc.contributor.authorStrydom, Christine
dc.contributor.authorAbolnik, Celia
dc.contributor.emailcelia.abolnik@up.ac.za
dc.date.accessioned2025-08-28T08:15:48Z
dc.date.available2025-08-28T08:15:48Z
dc.date.issued2025-05
dc.descriptionDATA AVAILABILITY : All the data generated have been detailed in Supplementary materials and sequence data was deposited in the Genbank database.
dc.description.abstractInfectious bronchitis virus (IBV) affects the respiratory, urogenital and reproductive systems of chickens and causes major economic losses. Biosecurity and vaccinations are used to limit the disease's impact, and identifying the circulating strains is important for selecting appropriate vaccines. The partial spike (S1) genes of 364 IBVs, isolated from commercial chickens in Botswana, Eswatini, Namibia and South Africa from 2010 to 2020, were phylogenetically analyzed. Seven genotypes were identified: 184 viruses (50,5 %) were classified as genotype GI-19 (QX) and 78 (21,4 %) were GI-1 (Mass/H120). Thirty-nine (10,7 %) were genotype GI-13 (4/91), 29 (8,0 %) were GVI-1 (TC07–2), 19 (5,2 %) were GI-23 (Variant 2), and 13 (3,6 %) were GI-11 (UFMG/G-Brazil). Two (0.5 %) viruses belonged to the GIV-1 (DE/072/92) genotype. Genotype GI-11 had not been reported outside South America before but has evidently circulated in South Africa for at least a decade. Similarly, genotype GVI-1, previously thought to be restricted to Asia, has been present in southern Africa since at least 2010. Prior to 2013, only Mass and H120 vaccines were permitted to be used in South Africa, but since 2013 793/B (GI-13), QX (GI-19), 4–91 (GI-13) and Variant 2 (GI-23) live attenuated vaccines were permitted. Accordingly, the four IBV variants we identified were putative recombinants of genotypes G1–1 and G1–19, G1–13 and G1–19, or G1–13 and unknown IBV strains, but these variant viruses did not spread extensively or persist in the region. The phylogenetic evidence points to imported contaminated poultry and poultry products as the source of new IBV genotypes in southern Africa. HIGHLIGHTS • Seven IBV genotypes circulated in southern African poultry from 2010 to 2020. • Genotype GI-11, thought to be restricted to South America, was identified. • Genotype GVI-1, thought to be restricted to Asia, was identified. • Variant IBVs were recombinants of registered vaccines and field viruses. • Imported poultry and poultry products are the likely source of IBVs.
dc.description.departmentProduction Animal Studies
dc.description.librarianhj2025
dc.description.sdgSDG-03: Good health and well-being
dc.description.sponsorshipThe National Research Foundation of South Africa.
dc.description.urihttps://www.elsevier.com/locate/virusres
dc.identifier.citationStrydom, C. & Abolnik, C. 2025, 'Seven infectious bronchitis virus genotypes including South American-origin G1-11 and Asian-origin GVI-1 circulated in southern African poultry from 2010 to 2020', Virus Research, vol. 355, art. 199568, pp. 1-8, doi : 10.1016/j.virusres.2025.199568.
dc.identifier.issn0168-1702 (print)
dc.identifier.issn1872-7492 (online)
dc.identifier.other10.1016/j.virusres.2025.199568
dc.identifier.urihttp://hdl.handle.net/2263/104036
dc.language.isoen
dc.publisherElsevier
dc.rights© 2025 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/)
dc.subjectInfectious bronchitis virus (IBV)
dc.subjectSpike protein
dc.subjectGenotype
dc.titleSeven infectious bronchitis virus genotypes including South American-origin G1-11 and Asian-origin GVI-1 circulated in southern African poultry from 2010 to 2020
dc.typeArticle

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