Role of plants in anticancer drug discovery

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Authors

Khazir, Jabeena
Mir, Bilal Ahmad
Pilcher, Lynne A.
Riley, Darren Lyall

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

Cancer is one of the major causes of death and the number of new cases, as well as the number of individuals living with cancer, is expanding continuously. Worldwide the alarming rise in mortality rate due to cancer has fuelled the pursuit for effective anticancer agents to combat this disease. Finding novel and efficient compounds of natural origin has been a major point of concern for research in the pharmaceutical sciences. Plants have been seen to possess the potential to be excellent lead structures and to serve as a basis of promising therapeutic agents for cancer treatment. Many successful anti-cancer drugs currently in use or their analogues are plant derived and many more are under clinical trials. This review aims to highlight the invaluable role that plants have played, and continue to play, in the discovery of anticancer agents.

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Keywords

Cancer, Drugs, Natural products, Plant derived anticancer drugs

Sustainable Development Goals

Citation

Khazir, J, Mir, BA, Pilcher, LA & Riley, DL 2014, 'Role of plants in anticancer drug discovery', Phytochemistry Letters, vol. 7, pp. 173-181.