Rapid molecular strategy for filovirus detection and characterization

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Authors

Zhai, Junhui
Palacios, Gustavo
Towner, Jonathan S.
Jabado, Omar
Kapoor, Vishal
Venter, Marietjie
Grolla, Allen
Briese, Thomas
Paweska, Janusz Tadeusz
Swanepoel, Robert

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Microbiology

Abstract

Filoviruses have the capacity to cause lethal outbreaks of hemorrhagic fever in primates. Here we present a simple consensus reverse transcription-PCR method for filovirus recognition and characterization and demonstrate its utility with all known filovirus strains. Phylogenetic assignment is achieved by automated web-based sequence analysis of amplification products.

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Keywords

Filoviruses, Phylogenetic

Sustainable Development Goals

Citation

Zhai, J, Palacios, G, Towner, JS, Jabado, O, Kapoor, V, Venter, M, Grolla, A, Briese, T, Paweska, J, Swanepoel, R, Feldmann, H, Nichol, ST & Lipkin WI 2007, ‘Rapid molecular strategy for filovirus detection and characterization’, Journal of Clinical Microbiology, vol. 45, no. 1, pp. 224-226. [http://jcm.asm.org/]