Drug-resistant tuberculosis in pet ring-tailed Lemur, Madagascar

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Authors

LaFleur, Marni
Reuter, Kim E.
Hall, Michael B.
Rasoanaivo, Hoby H.
McKernan, Stuart
Ranaivomanana, Paulo
Michel, Anita Luise
Rabodoarivelo, Marie Sylvianne
Iqbal, Zamin
Rakotosamimanana, Niaina

Journal Title

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Volume Title

Publisher

Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention

Abstract

We diagnosed tuberculosis in an illegally wild-captured pet ring-tailed lemur manifesting lethargy, anorexia, and cervical lymphadenopathy. Whole-genome sequencing confirmed the Mycobacterium tuberculosis isolate belonged to lineage 3 and harbored streptomycin resistance. We recommend reverse zoonosis prevention and determination of whether lemurs are able to maintain M. tuberculosis infection.

Description

We thank Madagascar Ministry of the Environment and Forests for permission to study ring-tailed lemurs (no. 155/19/MEDD/SG/DGEF/DGRNE) and the lemur facility for permission to conduct surgery and sample the sick ring-tailed lemurs.
Dr. LaFleur is an assistant professor at the University of San Diego, California, USA, and the founder and director of Lemur Love, a US-based nonprofit organization conducting research, conservation, and small-scale development in Madagascar. Her research examines the ecology of wild ring-tailed lemurs and the legal and illegal trades of wild-captured lemurs in Madagascar.

Keywords

Madagascar, Anthropozoonotic, Bacteria, Illegal, Lemur, Lineage 3, Lymph, Pet, Tuberculosis and other mycobacteria, Wildlife, Zoonoses, Tuberculosis (TB), Antimicrobial resistance (AMR)

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Citation

LaFleur, M., Reuter, K.E., Hall, M.B. et al. 2021, 'Drug-resistant tuberculosis in pet ring-tailed Lemur, Madagascar', Emerging Infectious Diseases, vol. 27, no. 3, pp. 977-979.