Establishing an alternative method for the quantitative analysis of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans by comprehensive two dimensional gas chromatography-time-of-flight mass spectrometry for developing countries
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Date
Authors
De Vos, Jayne
Gorst-Allman, Peter
Rohwer, Egmont Richard
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Comprehensive Gas Chromatography–Time-of-Flight Mass Spectrometry (GC×GC–TOFMS) methodology
has been refined for the analysis of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated
dibenzofurans (PCDFs) in samples with different matrices. This is specifically for application in developing
countries where access to gas chromatography–high resolution mass spectrometry (GC–HRMS)
and highly skilled personnel is limited. The method, using an Rxi-5 Sil MS column in the first dimension
(D) coupled with an Rtx-200 column in the second dimension (D), was used to quantify PCDDs
and PCDFs in different environmental sample matrices. The results were compared with those obtained
usingGC–HRMSand good agreement was observed. The limit of detection (LOD) for the method (300 fg on
column for spiked soil samples) was determined using an Rxi-XLB (1D) column coupled with an Rtx-200
column (D). Preliminary South African sample results are also discussed. Isomer specificity for different
tetrachloro dibenzo-p-dioxins (TCDDs) and tetrachloro dibenzofurans (TCDFs) was investigated using a
commercial standard. Adequate resolution was achieved. The method as described has great attraction
for developing countries being both financially and operationally favourable.
Description
Keywords
US EPA Method 1613, Polychloro dibenzo-p-dioxins (PCDDs), Polychloro dibenzofurans (PCDFs), Environmental pollutants, Dioxins and dioxin quantitation, Persistent organic pollutants (POPs)
Sustainable Development Goals
Citation
De Vos, J, Gorst-Allman, P & Rohwer E 2011, 'Establishing an alternative method for the quantitative analysis of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans by comprehensive two dimensional gas chromatography-time-of-flight mass spectrometry for developing countries', Journal of Chromatography A, vol. 1218, no. 21, pp.3282-3290.