The electrophoresis of the neurotropic virus of horsesickness and its neutralizing antibodies in low concentration
| dc.contributor.author | Polson, A. | |
| dc.contributor.editor | Du Toit, P.J. | |
| dc.date.accessioned | 2017-03-20T12:44:00Z | |
| dc.date.available | 2017-03-20T12:44:00Z | |
| dc.date.created | 2017 | |
| dc.date.issued | 1941 | |
| dc.description | The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. | en_ZA |
| dc.description.abstract | 1. By means of a modified form of the moving boundary method of electrophoresis of Tiselius, it was found possible to measure the rate of migration as well as the isoelectric points of viruses and their neutralizing antibodies in low concentrations. 2. The measurements were carried out on three antigenically different strains of horsesickness virus. It was found, within experimental error, that all three strains have the same isoelectric point as well as the same change of mobility with pH. 3. The similarity between the isoelectric points and the mobilities of serum albumin and horsesickness virus suggests a close relationship between the albumin and virus. The serum albumin can either be adsorbed on to the virus or the virus can have the same chemical composition as the albumin. 4. The mobilities and isoelectric points were determined of the neutralizing antibodies of strains 449 and OD. The same isoelectric point and the same change of mobility with pH were found for these two substances. 5. Attempts were made by means of electrophoresis on the separation of active virus from neutral virus antibody mixtures but with no success. | en_ZA |
| dc.identifier.citation | Polson, A 1941, 'The electrophoresis of the neurotropic virus of horsesickness and its neutralizing antibodies in low concentration’, Onderstepoort Journal of Veterinary Science and Animal Industry, vol. 16, nos. 1 & 2, pp. 51-66. | en_ZA |
| dc.identifier.issn | 0330-2465 | |
| dc.identifier.uri | http://hdl.handle.net/2263/59486 | |
| dc.language.iso | en | en_ZA |
| dc.publisher | Pretoria : The Government Printer | en_ZA |
| dc.rights | © 1941 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © 2017 University of Pretoria. Dept. of Library Services (digital). | en_ZA |
| dc.subject | Veterinary medicine | en_ZA |
| dc.subject.lcsh | Veterinary medicine -- South Africa | |
| dc.title | The electrophoresis of the neurotropic virus of horsesickness and its neutralizing antibodies in low concentration | en_ZA |
| dc.type | Article | en_ZA |