Evaluation of the phenolic and flavonoid contents and radical scavenging activity of three southern African medicinal plants

dc.contributor.authorSteenkamp, Vanessa
dc.contributor.authorNkwane, O.
dc.contributor.authorVan Tonder, Jacob John
dc.contributor.authorDinsmore, A.
dc.contributor.authorGulumian, Mary
dc.date.accessioned2014-07-15T07:26:02Z
dc.date.available2014-07-15T07:26:02Z
dc.date.issued2013-04-08
dc.description.abstractWarburgia salutaris (Bertol. F.) Chiovs, Rhoicissus tridentata (L.f.) Wild & Drum and Terminalia sericea (Burch. ex DC.), are widely used medicinal plants in southern Africa. The aim of the study was to determine the phenolic and flavonoid content and evaluate the antioxidant activity of the three medicinal plants. Total phenolic and flavonoid contents were determined spectrophotometrically as gallic acid and rutin equivalents, respectively. Individual phenolic acids were identified by means of gas chromatography-mass spectrometry. Antioxidant activities of the crude extracts were assessed using the TEAC assay. The highest phenolic content was detected in the crude methanol extract of the bark of W. salutaris and the highest flavonoid content was found in the crude methanol extract of the leaves of this plant. In all the studied plants the alkaline hydrolysable fraction yielded a greater variety of phenolic acids compared to the soluble/free phenolic acid fractions. The three medicinal plants investigated were found to be strong radical scavengers supporting the traditional use of these medicinal plants.en_US
dc.description.librarianam2014en_US
dc.description.sponsorshipThe Gauteng Department of Health and the National Research Foundation in South Africa.en_US
dc.description.urihttp://www.academicjournals.org/AJPPen_US
dc.identifier.citationSteenkamp, V, Nkwane, O, Van Tonder, J, Dinsmore, A & Gulumian, M 2013, 'Evaluation of the phenolic and flavonoid contents and radical scavenging activity of three southern African medicinal plants', African Journal of Pharmacy and Pharmacology, vol. 7, no. 13, pp. 703-709.en_US
dc.identifier.issn1996-0816
dc.identifier.other10.5897/AJPP12.1207
dc.identifier.urihttp://hdl.handle.net/2263/40740
dc.language.isoenen_US
dc.publisherAcademic Journalsen_US
dc.rights© 2013 Academic Journalsen_US
dc.subjectAntioxidant activityen_US
dc.subjectFlavonoidsen_US
dc.subjectMedicinal plantsen_US
dc.subjectPhenolic acidsen_US
dc.subjectPhenolic contenten_US
dc.subjectRhoicissus tridentataen_US
dc.subjectWarburgia salutarisen_US
dc.subjectTerminalia sericeaen_US
dc.titleEvaluation of the phenolic and flavonoid contents and radical scavenging activity of three southern African medicinal plantsen_US
dc.typeArticleen_US

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