A discordant pattern of uptake on Ga-68-PSMA PET/CT versus F-18-fluciclovine PET/CT in radiation-induced hepatitis implications for early postradiotherapy imaging-based response assessment

dc.contributor.authorAdediran, Omotayo A.
dc.contributor.authorLawal, Ismaheel Opeyemi
dc.contributor.authorMuzahir, Saima
dc.contributor.authorBhave, Manali A.
dc.contributor.authorFriend, Sarah
dc.contributor.authorFielder, Bridget
dc.contributor.authorMeisel, Jane
dc.contributor.authorTorres, Mylin A.
dc.contributor.authorStyblo, Toncred M.
dc.contributor.authorGraham, Cathy
dc.contributor.authorHolbrook, Anna
dc.contributor.authorKalinsky, Kevin
dc.contributor.authorCrowe, Ronald J.
dc.contributor.authorUlaner, Gary A.
dc.contributor.authorSchuster, David M.
dc.date.accessioned2023-11-08T04:47:35Z
dc.date.issued2023-04
dc.description.abstractA 62-year-old woman with right-sided invasive lobular breast carcinoma completed external beam radiotherapy 6 weeks before undergoing a 68Ga-PSMA PET/CT and 18F-fluciclovine PET/CT scan as part of an ongoing clinical trial (NCT04750473) assessing the performance of these molecular imaging modalities in invasive lobular breast carcinoma. The 68Ga-PSMA PET/CT demonstrated a band-like area of increased radiotracer uptake in the dome of the right lobe of the liver anteriorly, whereas 18F-fluciclovine PET/CT done a day later revealed photopenia in the corresponding area of the liver. The external beam radiotherapy plan confirmed that the radiotherapy field overlaid the region of the hepatic discordant radiotracer uptake on the PET/CT scans.en_US
dc.description.departmentNuclear Medicineen_US
dc.description.embargo2024-04-01
dc.description.librarianhj2023en_US
dc.description.urihttp://journals.lww.com/nuclearmed/pages/default.aspxen_US
dc.identifier.citationAdediran, O.A., Lawal, I.O., Muzahir, S. et al. 2023, 'A discordant pattern of uptake on Ga-68-PSMA PET/CT versus F-18-fluciclovine PET/CT in radiation-induced hepatitis implications for early postradiotherapy imaging-based response assessment', Clinical Nuclear Medicine, vol. 48, no. 4, pp. E202-E203, doi : 10.1097/RLU.0000000000004565.en_US
dc.identifier.issn0363-9762 (print)
dc.identifier.issn1536-0229 (online)
dc.identifier.other10.1097/RLU.0000000000004565
dc.identifier.urihttp://hdl.handle.net/2263/93193
dc.language.isoenen_US
dc.publisherLippincott Williams and Wilkinsen_US
dc.rights© 2023 Wolters Kluwer Health / Lippincott Williams & Wilkins. This is a non-final version of an article published in final form in Clinical Nuclear Medicine, vol. 48, no. 4, pp. E202-E203, 2023, doi : 10.1097/RLU.0000000000004565.en_US
dc.subject68Ga-PSMA PETen_US
dc.subjectPositron emission tomography (PET)en_US
dc.subject18F-fluciclovin PETen_US
dc.subjectRadiation hepatitisen_US
dc.subjectPET-based response assessment of radiotherapyen_US
dc.subjectLobular breast canceren_US
dc.subjectSDG-03: Good health and well-beingen_US
dc.subjectProstate specific membrane antigen (PSMA)en_US
dc.subjectPositron emission tomography/computed tomography (PET/CT)en_US
dc.titleA discordant pattern of uptake on Ga-68-PSMA PET/CT versus F-18-fluciclovine PET/CT in radiation-induced hepatitis implications for early postradiotherapy imaging-based response assessmenten_US
dc.typePostprint Articleen_US

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