Isolated posterior fossa involvement of progressive multifocal leucoencephalopathy in HIV : a case series with review of the literature
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Date
Authors
Mudau, Adziambei
Suleman, Farhana Ebrahim
Schutte, Clara-Maria
Lockhat, Zarina I.
Journal Title
Journal ISSN
Volume Title
Publisher
Health and Medical Publishing Group
Abstract
Progressive multifocal leucoencephalopathy (PML) is a progressive demyelinating
condition resulting from infection with the John Cunningham virus and precipitated
by immunocompromised states. The HIV pandemic, especially in sub-Saharan Africa, has
resulted in an increase in the number of patients presenting with PML. Imaging plays an
important role in diagnosis and the distribution of the disease is predominantly supratentorial.
Isolated posterior fossa involvement is a rare finding with very few cases described in the
literature. We present the largest case series of patients described in the literature, with isolated
posterior fossa involvement of PML, in HIV-positive patients.
Description
Keywords
Infection, Patients, Progressive multifocal leucoencephalopathy (PML), Human immunodeficiency virus (HIV), John Cunningham virus, HIV-positive patients
Sustainable Development Goals
Citation
Mudau A, Suleman FE,
Schutte CM, Lockhat ZI.
Isolated posterior fossa
involvement of progressive
multifocal
leucoencephalopathy in HIV:
A case series with review of
the literature. S Afr J Rad.
2017;21(2), a1262. https://
DOI.org/ 10.4102/sajr.v21i2.1262.