Molekulêre kruiskommunikasie tussen apoptose en outofagie geïnduseer deur ‘n 2-metoksiestradiol analoog (C19) in HeLa selle

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Authors

Theron, Anne Elisabeth
Visagie, M.H. (Michelle Helen)
Mqoco, T.V. (Thandi Vuyelwa)
Stander, Andre
Prudent, Renaud
Lafanechere, Laurence
Joubert, Annie M.

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Suid Afrikaanse Akademie vir Wetenskap & Kuns

Abstract

Using a novel synthesised sulphamoylated 2-methoxyestradiol analogue, C19, two types of cell death, namely apoptosis and autophagy, were demonstrated in vitro when cervical cancer HeLa cells were exposed to this compound.

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Keywords

HeLa selle, HeLa cells, Molekulêre kruiskommunikasie, Molecular crosstalk, Apoptose, Apoptosis, Outofagie, Autophagy, 2-Metoksiёstradiol analoog (C19), 2-Methoxyestradiol analogue (C19)

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Citation

Theron, A.E., Visagie, M., Mqoco, T., Stander, A., Prudent, R., Lafanechere, L. & Joubert, A.M., 2012, ‘Molekulêre kruiskommunikasie tussen apoptose en outofagie geïnduseer deur ‘n 2-metoksiёstradiol analoog (C19) in HeLa selle’, Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie 31(1), Art. #315, 1 page. http://dx.DOI.org/10.4102/satnt.v31i1.315