Molecular epidemiology of Rift Valley fever virus
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Date
Authors
Grobbelaar, Antoinette A.
Weyer, Jacqueline
Leman, Patricia A.
Kemp, Alan
Paweska, Janusz Tadeusz
Swanepoel, Robert
Journal Title
Journal ISSN
Volume Title
Publisher
Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention
Abstract
Phylogenetic relationships were examined for 198 Rift
Valley fever virus isolates and 5 derived strains obtained
from various sources in Saudi Arabia and 16 countries in
Africa during a 67-year period (1944–2010). A maximumlikelihood
tree prepared with sequence data for a 490-nt
section of the Gn glycoprotein gene showed that 95 unique
sequences sorted into 15 lineages. A 2010 isolate from a
patient in South Africa potentially exposed to co-infection
with live animal vaccine and wild virus was a reassortant.
The potential influence of large-scale use of live animal
vaccine on evolution of Rift Valley fever virus is discussed.
Description
Keywords
Rift Valley fever virus (RVFV)
Sustainable Development Goals
Citation
Grobbelaar, AA, Weyer, J, Leman, PA, Kemp, A, Paweska, JT & Swanepoel, R 2011, 'Molecular epidemiology of Rift Valley fever virus', Emerging Infectious Diseases, vol. 17, no. 12, pp. 2270-2276.