Human papillomavirus and carcinoma of the mucosal surfaces of the head and neck
| dc.contributor.author | Raubenheimer, E.J. (Erich) | |
| dc.contributor.author | Slavik, Tomas | |
| dc.contributor.author | Lemmer, Lou | |
| dc.contributor.author | Olivier, Henno | |
| dc.contributor.author | Van Heerden, Willem Francois Petrus | |
| dc.contributor.author | Miniggio, Hilde | |
| dc.date.accessioned | 2017-10-20T12:44:38Z | |
| dc.date.issued | 2018-01 | |
| dc.description.abstract | Human papillomavirus induced cervical cancer is the fourth most prevalent malignancy affecting females globally. Over the past two decades scientific information unveiled an increasing role for the virus in the pathogenesis of malignancies developing from the mucosal surfaces of the oropharynx. It is feasible to postulate that we may be in the beginning of a global pandemic of oropharyngeal cancer if the mode of transmission of the virus is taken into account. The main goals of this manuscript are to present a brief summary of the mechanisms of human papillomavirus induced malignant transformation, provide guidelines for the microscopic diagnosis of high risk human papillomavirus involvement in mucosal biopsies and highlight the implications thereof in cancers of the mucosal surfaces of the head and neck. | en_ZA |
| dc.description.department | Oral Pathology and Oral Biology | en_ZA |
| dc.description.embargo | 2019-01-01 | |
| dc.description.librarian | hj2017 | en_ZA |
| dc.description.uri | http://www.elsevier.com/locate/jomsmp | en_ZA |
| dc.identifier.citation | Raubenheimer, E., Slavik, T., Lemmer, L., Olivier, H., Van Heerden, W. & Miniggio, H. Human papillomavirus and carcinoma of the mucosal surfaces of the head and neck. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology (2018) 30(1):55-59, http://dx.doi.org/10.1016/j.ajoms.2017.08.003. NYP. | en_ZA |
| dc.identifier.issn | 2212-5558 (print) | |
| dc.identifier.issn | 2212-5566 (online) | |
| dc.identifier.other | 10.1016/j.ajoms.2017.08.003 | |
| dc.identifier.uri | http://hdl.handle.net/2263/62852 | |
| dc.language.iso | en | en_ZA |
| dc.publisher | Elsevier | en_ZA |
| dc.rights | © 2017 Asian AOMS, ASOMP, JSOP, JSOMS, JSOM, and JAMI. Notice : this is the author’s version of a work that was accepted for publication in Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, vol. 30, no. 1, pp. 55-59, 2018. doi : 10.1016/j.ajoms.2017.08.003. | en_ZA |
| dc.subject | High-risk HPV infection | en_ZA |
| dc.subject | HPV 16 | en_ZA |
| dc.subject | Oropharyngeal cancer | en_ZA |
| dc.subject | Human papillomavirus (HPV) | en_ZA |
| dc.subject | P16 | en_ZA |
| dc.title | Human papillomavirus and carcinoma of the mucosal surfaces of the head and neck | en_ZA |
| dc.type | Postprint Article | en_ZA |