Steriod-responsive idiopathic interstitial lung disease in two dogs

dc.contributor.authorKoster, Liza Sally
dc.contributor.authorKirberger, Robert M.
dc.date.accessioned2015-06-23T08:29:17Z
dc.date.available2015-06-23T08:29:17Z
dc.date.issued2014
dc.description.abstractTwo dogs had a 3 to 4 week history of persistent pyrexia, reduced exercise tolerance, inappetence and coughing and failed to respond to repeated courses of antibiotics. Clinical examination detected adventitious lung sounds, pyrexia and submandibular lymphadenopathy. Haematology in both dogs revealed an inflammatory leukogram. Both dogs had radiological abnormalities consistent with a multifocal interstitial lung pattern. Computed tomography performed in one dog had characteristic changes of cryptogenic organising pneumonia (COP), an extremely rare idiopathic interstitial lung disease. The abnormal pulmonary findings included several parenchymal bands, multifocal patchy ground-glass opacities and multifocal subpleural and peribronchial hyperattenuating poorly defined nodular opacities throughout the lungs. Bronchoalveolar lavage analysis in both dogs revealed a sterile suppurative exudate, excluding eosinophilic bronchopneumopathy. There was rapid resolution of clinical and radiological signs with corticosteroids and relapse in one dog after discontinuation of steroids supporting the diagnosis of this rare condition. Lung biopsy, which was not performed in either case, is definitive but considered invasive with major complications reported including death.en_ZA
dc.description.librarianhb2015en_ZA
dc.description.librarianab2016
dc.description.urihttp://vetrecordcasereports.bmj.comen_ZA
dc.identifier.citationKoster, LS & Kirberger, RM 2014, 'Steriod-responsive idiopathic interstitial lung disease in two dogs', Veterinary Record Case Reports, vol. 2, no. 1, pp. 1-6.en_ZA
dc.identifier.issn2052-6121
dc.identifier.other10.1136/vetreccr-2014-000091
dc.identifier.otherN-8699-2014
dc.identifier.other7004586182
dc.identifier.urihttp://hdl.handle.net/2263/45665
dc.language.isoenen_ZA
dc.publisherBMJ Publishing Groupen_ZA
dc.rights© 2014 by the BMJ Publishing Group Ltd. All rights reserved.en_ZA
dc.subjectLung diseaseen_ZA
dc.subjectDogsen_ZA
dc.subjectPyrexiaen_ZA
dc.subjectSubmandibular lymphadenopathy.en_ZA
dc.subjectInflammatory leukogramen_ZA
dc.subjectCryptogenic organising pneumonia (COP)en_ZA
dc.titleSteriod-responsive idiopathic interstitial lung disease in two dogsen_ZA
dc.typePostprint Articleen_ZA

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