Anticancer agents from diverse natural sources

dc.contributor.authorKhazir, Jabeena
dc.contributor.authorMir, Bilal Ahmad
dc.contributor.authorPilcher, Lynne A.
dc.contributor.authorRiley, Darren Lyall
dc.contributor.authorCowan, Don A.
dc.date.accessioned2017-03-14T12:03:15Z
dc.date.available2017-03-14T12:03:15Z
dc.date.issued2014-11
dc.description.abstractCancer is one of the major causes of death and the number of new cases, as well as the number of individuals living with cancer, is expanding continuously. Worldwide the alarming rise in mortality rate due to cancer has fuelled the pursuit for effective anticancer agents to combat this disease. Finding novel and efficient compounds of natural origin has been a major point of concern for research in the pharmaceutical sciences. Natural products have been seen to possess the potential to be excellent lead structures and to serve as a basis of promising therapeutic agents for cancer treatment. Many successful anti-cancer drugs currently in use are natural products or their analogues and many more are under clinical trials. This review aims to highlight the invaluable role that natural products have played, and continue to play, in the discovery of anticancer agents and also summarizes the recently launched natural product-derived anticancer drugs and new natural product templates in clinical pipeline.en_ZA
dc.description.departmentChemistryen_ZA
dc.description.departmentGeneticsen_ZA
dc.description.librarianhb2017en_ZA
dc.description.sponsorshipUniversity of Pretoriaen_ZA
dc.description.urihttp://www.naturalproduct.us/en_ZA
dc.identifier.citationKhazir, J, Mir, BA, Pilcher, L, Riley, D & Cowan, DA 2014, 'Anticancer agents from diverse natural sources', Natural Product Communications, vol. 9, no. 11, pp. 1655-1669.en_ZA
dc.identifier.issn1934-578X (print)
dc.identifier.issn1555-9475 (online)
dc.identifier.urihttp://hdl.handle.net/2263/59424
dc.language.isoenen_ZA
dc.publisherNatural Producten_ZA
dc.rightsNatural Product. This is a preprint of Anticancer agents from diverse natural sources, Natural Product Communications, vol. 9, no. 11, pp. 1655-1669. Natural Product Communications is available online at : http://www.naturalproduct.us.en_ZA
dc.subjectCanceren_ZA
dc.subjectDrugsen_ZA
dc.subjectEndophytesen_ZA
dc.subjectMarine organismsen_ZA
dc.subjectNatural productsen_ZA
dc.subjectPlant derived anticancer drugsen_ZA
dc.titleAnticancer agents from diverse natural sourcesen_ZA
dc.typePostprint Articleen_ZA

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