Adverse drug reaction reporting by healthcare providers in sub-Saharan Africa : a scoping review of the challenges faced and the strategies to address the challenges

dc.contributor.authorMoyo, Enos
dc.contributor.authorMoyo, Perseverance
dc.contributor.authorMangoya, Derek
dc.contributor.authorImran, Mohd
dc.contributor.authorDzinamarira, Tafadzwa
dc.date.accessioned2024-05-14T09:39:23Z
dc.date.available2024-05-14T09:39:23Z
dc.date.issued2023
dc.description.abstractBACKGROUND : Preventable adverse drug reactions (ADR) and adverse events following immunization (AEFI) are more prevalent in patients of low- and middle-income nations compared to high-income countries. Sub-Saharan Africa (SSA) experiences more ADR and AEFI for many reasons, including poor quality control of drug products, extensive use of substandard traditional and herbal medicines, environmental influences, and genetic factors. This scoping review aimed to explore the challenges to ADR and AEFI reporting by healthcare providers in SSA and strategies that can be used to address these challenges. METHODS : In this scoping review, articles reporting on primary research conducted in SSA to identify challenges to ADR and AEFI reporting and strategies to address these challenges, and published in English, were retrieved from three databases (Google Scholar, ScienceDirect, and PubMed). The quality of the selected quantitative studies was evaluated utilizing the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) 22-item checklist. In contrast, qualitative studies were evaluated for credibility, confirmability, dependability, and transferability. The guidelines specified in the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols (PRISMA-P) statement were followed in this scoping review. RESULTS : This review revealed several challenges to ADR and AEFI reporting in SSA. The challenges were categorized into healthcare provider-related, work-related, material/tools-related, and national pharmacovigilance activities-related challenges. Several strategies to address the challenges were also revealed and categorized into healthcare providers, reporting material/tools and mechanisms strategies, national or institutional pharmacovigilance, and community engagement strategies. CONCLUSION : Countries in SSA face several challenges to ADR and AEFI reporting. Strategies identified to improve the reporting of ADR and AEFI should be prioritized so that unnecessary morbidity and mortality are avoided in the region.en_US
dc.description.departmentSchool of Health Systems and Public Health (SHSPH)en_US
dc.description.librarianhj2024en_US
dc.description.sdgSDG-03:Good heatlh and well-beingen_US
dc.description.urihttps://www.elsevier.com/locate/ijansen_US
dc.identifier.citationMoyo, E., Moyo, P., Mangoya, D. et al. 2023, 'Adverse drug reaction reporting by healthcare providers in sub-Saharan Africa: a scoping review of the challenges faced and the strategies to address the challenges', International Journal of Africa Nursing Sciences, vol. 19, art. 100639, pp. 1-10, doi : 10.1016/j.ijans.2023.100639.en_US
dc.identifier.issn2214-1391 (online)
dc.identifier.other10.1016/j.ijans.2023.100639
dc.identifier.urihttp://hdl.handle.net/2263/95950
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.rights© 2023 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license.en_US
dc.subjectAdverse drug reaction (ADR)en_US
dc.subjectAdverse events following immunization (AEFI)en_US
dc.subjectSub-Saharan Africa (SSA)en_US
dc.subjectAdverse drug reactions reportingen_US
dc.subjectHealthcare providersen_US
dc.subjectChallengesen_US
dc.subjectStrategiesen_US
dc.subjectSDG-03: Good health and well-beingen_US
dc.titleAdverse drug reaction reporting by healthcare providers in sub-Saharan Africa : a scoping review of the challenges faced and the strategies to address the challengesen_US
dc.typeArticleen_US

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