Total synthesis of isoflavonoids

dc.contributor.authorSelepe, Mamoalosi A.
dc.contributor.authorMthembu, Siyanda T.
dc.contributor.authorSonopo, Molahlehi S.
dc.contributor.emailmamoalosi.selepe@up.ac.za
dc.date.accessioned2026-02-13T08:22:32Z
dc.date.available2026-02-13T08:22:32Z
dc.date.issued2025-03
dc.descriptionThis article is part of the themed collection: Emerging Investigator Review series. DATA AVAILABILITY : No primary research results, software or code have been included and no new data were generated or analysed as part of this review.
dc.description.abstractIsoflavonoids are phenolic compounds with wide structural diversity and a plethora of biological activities. Owing to their structural variation and potential health-promoting and other benefits, they have been targeted for synthesis. Herein, we review the synthesis of natural isoflavonoids belonging to different classes that include isoflavones, isoflavanones, isoflavans, isoflavenes, pterocarpans, rotenoids, coumaronochromones, and coumestans. The synthetic methodologies employed and advancements in synthetic strategies are highlighted.
dc.description.departmentChemistry
dc.description.librarianhj2026
dc.description.sdgSDG-12: Responsible consumption and production
dc.description.sponsorshipSupported by the National Research Foundation of South Africa through Thuthuka funding; the University of Pretoria and the Department of Higher Education and Training (Republic of South Africa) for support through University Staff Capacity Programme (UCDP).
dc.description.urihttps://pubs.rsc.org/en/journals/journal/np
dc.identifier.citationSelepe, M.A., Mthembu, S.T. & Sonopo, M.S. 2025, 'Total synthesis of isoflavonoids', Natural Product Reports, vol. 42, no. 3, pp. 540-591, doi : 10.1039/d4np00060a.
dc.identifier.issn0265-0568 (print)
dc.identifier.issn1460-4752 (online)
dc.identifier.other10.1039/d4np00060a
dc.identifier.urihttp://hdl.handle.net/2263/108207
dc.language.isoen
dc.publisherRoyal Society of Chemistry
dc.rights© The Royal Society of Chemistry 2025. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
dc.titleTotal synthesis of isoflavonoids
dc.typeArticle

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Selepe_Total_2025.pdf
Size:
8.3 MB
Format:
Adobe Portable Document Format
Description:
Article

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: