Comparison of quality of induction of anaesthesia between intramuscularly administered ketamine, intravenously administered ketamine and intravenously administered propofol in xylazine premedicated cats

dc.contributor.authorDzikiti, Tarisai Brighton
dc.contributor.authorChanaiwa, S.
dc.contributor.authorMponda, P.
dc.contributor.authorSigauke, C.
dc.contributor.authorDzikiti, Loveness Nyaradzo
dc.contributor.emailbrighton.dzikiti@up.ac.zaen
dc.date.accessioned2008-05-06T08:07:48Z
dc.date.available2008-05-06T08:07:48Z
dc.date.issued2007-12
dc.description.abstractThe quality of induction of general anesthesia produced by ketamine and propofol, 2 of the most commonly used anaesthetic agents in cats, was assessed. Eighteen cats admitted for elective procedures were randomly assigned to 3 groups and then premedicated with xylazine 0.75 mg/kg intramuscularly before anaesthesia was induced with ketamine 15 mg/kg intramuscularly (KetIM group), ketamine 10 mg/kg intravenously (KetIV group) or propofol 4 mg/kg intravenously (PropIV group). Quality of induction of general anaesthesia was determined by scoring ease of intubation, degree of struggling, and vocalisation during the induction period. The quality of induction of anaesthesia of intramuscularly administered ketamine was inferior to that of intravenously administered ketamine, while intravenously administered propofol showed little difference in quality of induction from ketamine administered by both the intramuscular and intravenous routes. There were no significant differences between groups in the ease of intubation scores, while vocalisation and struggling were more common in cats that received ketamine intramuscularly than in those that received intravenously administered ketamine or propofol for induction of anaesthesia. Laryngospasms occurred in 2 cats that received propofol. The heart rates and respiratory rates decreased after xylazine premedication and either remained the same or decreased further after induction for all 3 groups, but remained within normal acceptable limits. This study indicates that the 3 regimens are associated with acceptable induction characteristics, but administration of ketamine intravenously is superior to its administration intramuscularly and laryngeal desensitisation is recommended to avoid laryngospasms.en
dc.format.extent154141 bytes
dc.format.mimetypeapplication/pdf
dc.identifier.citationDzikiti, TB, Chanaiwa, S, Mponda, P, Sigauke, C & Dzikiti, LN 2007, 'Comparison of quality of induction of anaesthesia between intramuscularly administered ketamine, intravenously administered ketamine and intravenously administered propofol in xylazine premedicated cats', Journal of the South African Veterinary Association, vol. 78, no. 4, pp. 201-204. [http://www.journals.co.za/ej/ejour_savet.html]en
dc.identifier.issn0038-2809
dc.identifier.other27967665100
dc.identifier.otherN-8696-2014
dc.identifier.urihttp://hdl.handle.net/2263/5126
dc.language.isoenen
dc.publisherSouth African Veterinary Associationen
dc.rightsSouth African Veterinary Associationen
dc.subjectCatsen
dc.subjectKetamineen
dc.subjectPropofol anaesthesiaen
dc.subject.lcshAnimal anesthesiaen
dc.subject.lcshVeterinary anesthesiaen
dc.subject.lcshCats -- Diseasesen
dc.titleComparison of quality of induction of anaesthesia between intramuscularly administered ketamine, intravenously administered ketamine and intravenously administered propofol in xylazine premedicated catsen
dc.typeArticleen

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